Evidence map›Paper›PMID 39487366›Full record

ReviewNature cardiovascular research2024

Concealed cardiomyopathy as an emerging cause of sudden cardiac arrest and sudden cardiac death.

Julia C Isbister, Rafik Tadros, Hariharan Raju, Christopher Semsarian

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature cardiovascular research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Brugada Syndrome: an exemplar for the genomic basis of sudden death.European journal of human genetics : EJHG · 2026
    Review
  4. Quantitative Histological Insights Into Sudden Arrhythmic Death Syndrome: Findings From a Forensic Autopsy Cohort.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026
    Article
  5. Screening families after sudden cardiac death in the young: do we ever stop?Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Julia C IsbisterFaculty of Medicine and Heath, the University of Sydney, Sydney, New South Wales, Australia.
Rafik TadrosCardiovascular Genetics Center, Montreal Heart Institute, Montreal, Québec, Canada.ORCID http://orcid.org/0000-0002-1472-0258
Hariharan RajuFaculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, New South Wales, Australia.
Christopher SemsarianFaculty of Medicine and Heath, the University of Sydney, Sydney, New South Wales, Australia. christopher.semsarian@sydney.edu.au.ORCID http://orcid.org/0000-0001-6441-274X

Funding

Department of Health | National Health and Medical Research Council (NHMRC) 2016822
6 · The paper itself

Abstract

The inherited cardiomyopathies exhibit a broad spectrum of disease, with some patients remaining asymptomatic throughout life, while, for others, the first symptom of disease is sudden cardiac death at a young age. The risk of malignant ventricular arrhythmia in these conditions has traditionally been linked to the degree of structural myocardial abnormalities and functional impairment. However, recent advances in genetic testing and knowledge of the genetic basis of the diseases have led to the identification of concealed cardiomyopathy, in which sudden cardiac arrest or sudden cardiac death occurs in the absence of observable clinical features of cardiomyopathy, with a diagnosis being made only after the identification of a causative genetic variant. Increased awareness of concealed cardiomyopathy, a better understanding of mechanisms of arrhythmia and identification of risk modulators will be vital to improve care for families with concealed cardiomyopathy.

Indexed as

CardiomyopathiesDeath, Sudden, CardiacArrhythmias, CardiacGenetic Predisposition to DiseaseGenetic TestingHumansRisk Factors

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.