Evidence map›Paper›PMID 39490440›Full record

ArticleThe American journal of pathology2025

Peroxisome Proliferator-Activated Receptor α/γ and Cannabinoid Receptor 2 Agonist Attenuated Nonalcoholic Steatohepatitis Exosome-Related Abnormalities in Mice.

Chia-Chang Huang, Ching-Hsiang Wang, Hsiao-Yun Yeh, Hung-Cheng Tsai, Ching-Wen Yang, Tzu-Hao Li, Chien-Wei Su, Ying-Ying Yang, Han-Chieh Lin, Ming-Chih Hou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chia-Chang HuangDepartment of Medical Education, Taipei Veterans General Hospital, Taipei City, Taiwan; Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei City, Taiwan.
Ching-Hsiang WangDepartment of Medical Education, Taipei Veterans General Hospital, Taipei City, Taiwan.
Hsiao-Yun YehDepartment of Medical Education, Taipei Veterans General Hospital, Taipei City, Taiwan; Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei City, Taiwan.
Hung-Cheng TsaiFaculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei City, Taiwan; Division of Allergy, Immunology, and Rheumatology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan.
Ching-Wen YangDepartment of Medical Education, Taipei Veterans General Hospital, Taipei City, Taiwan.
Tzu-Hao LiDepartment of Internal Medicine, Shin Kong Wu Ho-Su Memorial Foundation Hospital, Taipei City, Taiwan; School of Medicine, College of Medicine, Fu Jen Catholic University, Taipei City, Taiwan.
Chien-Wei SuDivision of Allergy, Immunology, and Rheumatology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan.
Ying-Ying YangDepartment of Medical Education, Taipei Veterans General Hospital, Taipei City, Taiwan; Faculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei City, Taiwan. Electronic address: yangyy@vghtpe.gov.tw.
Han-Chieh LinDivision of Allergy, Immunology, and Rheumatology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan.
Ming-Chih HouFaculty of Medicine, School of Medicine, National Yang-Ming Chiao Tung University, Taipei City, Taiwan; Division of Allergy, Immunology, and Rheumatology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study explored the mechanisms and effects of 1 month of peroxisome proliferator-activated receptor (PPAR)α/γ agonist aleglitazar (10 mg/kg per day) or cannabinoid receptor 2 (CB

Indexed as

Cannabinoid Receptor AgonistsExosomesIndolesNon-alcoholic Fatty Liver DiseasePPAR alphaPPAR gammaReceptor, Cannabinoid, CB2AnimalsDiet, High-FatInflammationIntra-Abdominal FatMaleMiceMice, Inbred C57BLCannabinoid Receptor AgonistsIndolesiodopravadolinePPAR alphaPPAR gammaReceptor, Cannabinoid, CB2

Identifiers

PMID39490440
PMCPMC12179500

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.