Evidence mapPaperPMID 39491719Full record

ArticleContemporary clinical trials2024

The Risk Information and Skin-cancer Education for Undergraduate Prevention (RISE-UP) Study: Protocol for a Trial of Personalized Sun Protection Interventions for Skin Cancer Prevention among Undergraduate Students.

Yelena P Wu, Liberty A Woodside, Kimberly A Kaphingst, Jakob D Jensen, Jada G Hamilton, Wendy Kohlmann, Ben Haaland, Ben J Brintz, Siobhan M Phillips, Jennifer L Hay

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05634252 (Risk Information and Skin-Cancer Education and Undergraduate Prevention Trial), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05634252 phase3active not recruitingnot on this map

Risk Information and Skin-Cancer Education and Undergraduate Prevention Trial

TypeinterventionalSponsorUniversity of UtahRan2023 to 2027Enrolled528ConditionsSkin CancerArmsEducation, Action Plan, UV Photo, MC1R Test
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yelena P WuDepartment of Dermatology, University of Utah, 30 North 1900 East, 4A330, Salt Lake City, UT 84132, USA; Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope Drive, Salt Lake City, UT 84112, USA. Electronic address: yelena.wu@utah.edu.
Liberty A WoodsideHuntsman Cancer Institute, University of Utah, 2000 Circle of Hope Drive, Salt Lake City, UT 84112, USA. Electronic address: liberty.woodside@hci.utah.edu.
Kimberly A KaphingstHuntsman Cancer Institute, University of Utah, 2000 Circle of Hope Drive, Salt Lake City, UT 84112, USA; Department of Communication, University of Utah, 255 S Central Campus Dr., Rm 2400, Salt Lake City, UT 84112, USA. Electronic address: kim.kaphingst@hci.utah.edu.
Jakob D JensenHuntsman Cancer Institute, University of Utah, 2000 Circle of Hope Drive, Salt Lake City, UT 84112, USA; Department of Communication, University of Utah, 255 S Central Campus Dr., Rm 2400, Salt Lake City, UT 84112, USA. Electronic address: jakob.jensen@bsh.utah.edu.
Jada G HamiltonDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 633 Third Avenue, NY, New York 10017, USA. Electronic address: hamiltoj@mskcc.org.
Wendy KohlmannHuntsman Cancer Institute, University of Utah, 2000 Circle of Hope Drive, Salt Lake City, UT 84112, USA. Electronic address: wendy.kohlmann@hci.utah.edu.
Ben HaalandHuntsman Cancer Institute, University of Utah, 2000 Circle of Hope Drive, Salt Lake City, UT 84112, USA. Electronic address: bhaaland@pentaracorp.com.
Ben J BrintzDepartment of Internal Medicine, University of Utah, 30 N Mario Capecchi Dr, 3(rd) Floor, Salt Lake City, UT 84112, USA. Electronic address: ben.brintz@hsc.utah.edu.
Siobhan M PhillipsDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Drive Suite 1400, Chicago, IL 60611, USA. Electronic address: smphillips@northwestern.edu.
Jennifer L HayDepartment of Psychiatry and Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 633 Third Avenue, NY, New York 10017, USA. Electronic address: hayj@mskcc.org.

Funding

The Patient-Reported Outcomes, Community-Engagement and Language (PRO-CEL) CoreP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · 1985 to 2025
$88.4M
UTAH REGIONAL CANCER CENTERP30CA042014 · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · 1986 to 2025
$11.4M
CTSA UM1 Program at University of UtahUM1TR004409 · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · 2025 to 2025
$5.4M
Optimization of a personalized skin cancer risk intervention for at-risk young adultsR01CA266302 · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · 2025 to 2025
$540k
NCATS NIH HHS UM1 TR004409NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA042014NCI NIH HHS R01 CA266302
6 · The paper itself

Abstract

backgroundAddressing the increasing incidence of skin cancer among young adults is a priority. The objective of the Risk Information and Skin-cancer Education for Undergraduate Prevention (RISE-UP) study is to identify personalized intervention components to prevent sunburn, a clinically significant outcome highly associated with skin cancer, in college students.

methodsGuided by the Elaboration Likelihood Model, the study will use Multiphase Optimization Strategy (MOST) methodology to test three intervention components (ultraviolet photography, MC1R genetic testing, and action planning) each with two levels (yes v. no) in a full-factorial experiment to evaluate unique and combined effects of these components to improve outcomes over the longer-term, with seasonally timed follow-up. At-risk University of Utah students (N = 528) will be recruited. Eligibility criteria include self-reported sunburn or tanning in the past year, or not utilizing recommended sun protection. After baseline assessment, participants will be randomized to intervention group, stratified by sex. Assessments will be completed at (1) Baseline; (2) Intervention; (3) 1 month after intervention; (4) 4 months after intervention (the end of the first summer); and (5) 15 months after intervention (the end of the second summer). The primary outcome will be participants' self-reported number of sunburns. Secondary outcomes will include self-reported sun protection and tanning behaviors and, in a randomly selected subgroup, an objective measure of ultraviolet radiation (UVR) exposure.

conclusionThe RISE-UP study will determine the efficacy of different combinations of personalized skin cancer preventative interventions for young adults and determine the optimal combination of intervention components to prevent skin cancer. CLINICAL

trial registrationNCT05634252.

Indexed as

Skin NeoplasmsStudentsSunburnSunscreening AgentsAdolescentAdultFemaleGenetic TestingHealth EducationHumansMalePhotographyReceptor, Melanocortin, Type 1Ultraviolet RaysUniversitiesUtahMC1R protein, humanReceptor, Melanocortin, Type 1Sunscreening AgentsCollegeMelanomaPreventionRisk perceptionSkin cancerYoung adult

Identifiers

PMID39491719
PMCPMC11620905

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.