Evidence map›Paper›PMID 39493576›Full record

ArticleFrontiers in bioinformatics2024

Identification of novel drug targets for

Narjes Noori Goodarzi, Mahshid Khazani Asforooshani, Behzad Shahbazi, Nayereh Rezaie Rahimi, Farzad Badmasti

Abstract read
In one paragraph

Article in Frontiers in bioinformatics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Determination of Potential Inhibitors againstCurrent pharmaceutical design · 2026
    Review
  3. Article
  4. Article
  5. TargetingFrontiers in cellular and infection microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Narjes Noori GoodarziDepartment of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Mahshid Khazani AsforooshaniDepartment of Bacteriology, Pasteur Institute of Iran, Tehran, Iran.
Behzad ShahbaziSchool of Pharmacy, Semnan University of Medical Sciences, Semnan, Iran.
Nayereh Rezaie RahimiDepartment of environmental Health Engineering, School of Public Health, Shiraz University of Medical Sciences, Shiraz, Iran.
Farzad BadmastiDepartment of Bacteriology, Pasteur Institute of Iran, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: Core-proteome analysis of 132 Results: A total of 54 novel drug targets with desirable properties were identified. DAH7PS was selected for further investigation, and virtual screening of StreptomeDB compounds yielded 36 high-affinity binding of the ligands. Two small molecules, 6,8-Dihydroxyisocoumarin-3-carboxylic acid and Epicatechin, also showed favorable RO5 and ADMET properties. MD simulations confirmed the stability and reliability of DAH7PS-ligand complexes, indicating their potential as inhibitors. Conclusion: This study identified 54 novel drug targets against

Indexed as

DAH7PSHelicobacter pylorishikimate pathwayStreptomeDBstructure-based virtual screening

Identifiers

PMID39493576
PMCPMC11527725

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.