Evidence map›Paper›PMID 39494823›Full record

ReviewInternational journal of technology assessment in health care2024

Ethical challenges for Health Technology Assessment (HTA) in the evolving evidence landscape.

Pietro Refolo, Katherine Duthie, Björn Hofmann, Michal Stanak, Neil Bertelsen, Bart Bloemen, Rosella Di Bidino, Wija Oortwijn, Costanza Raimondi, Dario Sacchini and 2 more

Abstract readReview
In one paragraph

Review in International journal of technology assessment in health care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Integrating ethical analysis in health technology assessment: opportunities and challenges.International journal of technology assessment in health care · 2026
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Pietro RefoloDepartment of Healthcare Surveillance and Bioethics, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID https://orcid.org/0000-0003-1055-160X
Katherine DuthieJohn Dossetor Health Ethics Centre, University of Alberta, Edmonton, AB, Canada.
Björn HofmannDepartment of Health Science, Norwegian University of Science and Technology, Gjøvik, Norway.ORCID https://orcid.org/0000-0001-6709-4265
Michal StanakNational Institute for Value and Technologies in Healthcare (NIHO), Bratislava, Slovak Republic.ORCID https://orcid.org/0000-0003-0313-0997
Neil BertelsenHealth Technology Assessment international (HTAi) Patient & Citizen Involvement, Neil Bertelsen Consulting, Berlin, Germany.
Bart BloemenDepartment for Health Evidence, Radboud University Medical Centre, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0001-8856-2216
Rosella Di BidinoFondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.ORCID https://orcid.org/0000-0001-9773-856X
Wija OortwijnDepartment for Health Evidence, Radboud University Medical Centre, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0003-4499-8602
Costanza RaimondiDepartment of Healthcare Surveillance and Bioethics, Università Cattolica del Sacro Cuore, Rome, Italy.
Dario SacchiniDepartment of Healthcare Surveillance and Bioethics, Università Cattolica del Sacro Cuore, Rome, Italy.ORCID https://orcid.org/0000-0002-1581-3018
Gert Jan van der WiltDepartment for Health Evidence, Radboud University Medical Centre, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0002-5856-762X
Kenneth BondDepartment of Health, Medicine, and Caring Sciences, Linköping University, Linköping, Sweden.ORCID https://orcid.org/0000-0002-7620-9375

Funding

Health Technology Assessment international Call for Group of Interest 2022
6 · The paper itself

Abstract

Since its inception, Health Technology Assessment (HTA) has typically determined the value of a technology by collecting information derived from randomized clinical trials (RCTs), in line with the principles of evidence-based medicine (EBM). However, data from RCTs did not constitute the sole source of information, as other types of evidence (such as primary qualitative research) have often been utilized. Recent advances in both generating and collecting other types of evidence are broadening the landscape of evidence, adding complexity to the discussion of "robustness of evidence." What are the consequences of these recent developments for the methodology and conduct of HTA, the HTA community, and its ethical commitments? The aim of this article is to explore some ethical challenges that are emerging in the current evolving evidence landscape, particularly changes in evidence generation and collection (e.g., diversification of data sources), and shifting standards of evidence in the field of HTA (e.g., increasing acceptability of evidence that is thought of as lower quality). Our conclusion is that deciding how to best maintain trustworthiness is common to all these issues.

Indexed as

Evidence-Based MedicineTechnology Assessment, BiomedicalData CollectionHumansRandomized Controlled Trials as Topicartificial intelligenceethicsevidence-based medicinerandomized controlled trial

Identifiers

PMID39494823
PMCPMC11569911

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.