Evidence map›Paper›PMID 39495353›Full record

ArticleInternal and emergency medicine2025

The impact of lactose intolerance diagnosis: costs, timing, and quality-of-life.

Simona Dominici, Nico Donati, Sofia Menabue, Michele Di Stefano, Maria Sole Facioni

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In one paragraph

Article in Internal and emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Simona DominiciELLEFREE S.R.L., Polo Tecnologico Lucchese, 55100, Lucca, Italy.
Nico DonatiRegistered Dietitian, Centro Di Riferimento Regionale Per La Celiachia Dell'Adulto, Careggi, 50134, Firenze, Italy.
Sofia MenabueDepartment of Pharmacy, University of Pisa, 56126, Pisa, Italy.
Michele Di StefanoDepartment of Internal Medicine, IRCCS S. Matteo Hospital Foundation, Pavia, Italy. m.distefano@unipv.it.
Maria Sole FacioniAILI-Associazione Italiana Latto-Intolleranti Aps, 55100, Lucca, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactose intolerance (LI) is a very common condition but, despite many efforts of the Italian National Health Service to reduce diagnostic delay of chronic disorders and provide prompt treatments, its early diagnosis remains an unmet need. In addition, the COVID-19 pandemic has exacerbated this problem, due to the conversion of many public health services to COVID centers. This study aims to analyze the diagnostic journey of patients suffering from LI, taking into account the duration of the process, associated costs, and impact on quality of life. Anonymous surveys were designed and distributed to patients with LI as well as physicians involved in LI management. The data were analyzed to determine the time required for a reliable LI diagnosis and average costs. Diagnostic delay of LI proved to be longer than 2 years, its impact on quality of life proved to be moderate to high in most of participants, especially in their psychosocial domain, and average costs proved to be high. Further investigations are needed to determine the economic burden of maintaining an asymptomatic status in patients with LI.

Indexed as

Lactose IntoleranceQuality of LifeAdultAgedCOVID-19Delayed DiagnosisFemaleHumansItalyMaleMiddle AgedSurveys and QuestionnairesTime FactorsDiagnosis costDiagnosis delayDisease burdenLactose intolerancePublic healthcareQuality of life

Identifiers

PMID39495353

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.