Evidence mapPaperPMID 39495753Full record

ArticlePloS one2024

Lack of sex-specific differences in the associations between the dimensions of great vessels and exercise performance in amateur cyclists.

Michał J Pytka, Remigiusz A Domin, Mikołaj S Żołyński, Jan Niziński, Tomasz Krauze, Barbara Więckowska, Andrzej Wykrętowicz, Przemysław Guzik

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Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Michał J PytkaDepartment of Cardiology - Intensive Therapy, Poznan University of Medical Sciences, Poznań, Poland.ORCID https://orcid.org/0000-0002-8418-0090
Remigiusz A DominUniversity Centre for Sports and Medical Studies, Poznan University of Medical Sciences, Poznań, Poland.
Mikołaj S ŻołyńskiDepartment of Cardiology - Intensive Therapy, Poznan University of Medical Sciences, Poznań, Poland.
Jan NizińskiUniversity Centre for Sports and Medical Studies, Poznan University of Medical Sciences, Poznań, Poland.ORCID https://orcid.org/0000-0002-5455-3845
Tomasz KrauzeDepartment of Cardiology - Intensive Therapy, Poznan University of Medical Sciences, Poznań, Poland.
Barbara WięckowskaDepartment of Computer Science and Statistics, Poznan University of Medical Sciences, Poznań, Poland.
Andrzej WykrętowiczDepartment of Cardiology - Intensive Therapy, Poznan University of Medical Sciences, Poznań, Poland.
Przemysław GuzikDepartment of Cardiology - Intensive Therapy, Poznan University of Medical Sciences, Poznań, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndurance training enhances exercise capacity and triggers cardiovascular adaptations in both males and females. We investigated the relationship between the dimensions of great vessels and exercise capacity in amateur cyclists while considering sex differences.

methodsUsing resting transthoracic echocardiography, we measured the dimensions of the main pulmonary artery (PA), aorta, and inferior vena cava (IVC) in 190 participants, who subsequently underwent a cardiopulmonary exercise test (CPET) until exhaustion.

resultsThe mean age of study participants was 30 years. Males (71%) exhibited a larger aortic annulus (approximately 3.5 mm, p<0.0001) and PA diameter (2.4 mm, p<0.0001) than females. No significant sex differences were found in expiratory or inspiratory IVC diameters. Males achieved greater peak exercise capacity, including workload, O2 consumption (VO2), and O2 pulse. Aortic and PA dimensions showed strong correlations with energy expenditure, workload, VO2, and O2 pulse. However, these correlations weakened when analyzed separately by sex. Multivariate linear regression revealed associations between CPET results, vessels size, and sex, with sex differences observed only in the intercepts-not in interactions between sex and vessels size. Despite males having better CPET results and larger vessels, the relationships between peak exercise capacity parameters and vessel dimensions were similar in both sexes.

conclusionLarger vessel dimensions (of the aorta, PA, and IVC) were associated with greater peak exercise capacity in amateur cyclists, with no significant sex differences in these associations.

Indexed as

BicyclingExercise TestAdultAortaEchocardiographyExerciseExercise ToleranceFemaleHumansMaleOxygen ConsumptionPulmonary ArterySex CharacteristicsSex FactorsVena Cava, InferiorYoung Adult

Identifiers

PMID39495753
PMCPMC11534209

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