Evidence map›Paper›PMID 39496559›Full record

ArticleJournal of child psychology and psychiatry, and allied disciplines2025

Callous-unemotional traits, cognitive functioning, and externalizing problems in a propensity-matched sample from the ABCD study.

Kristin Murtha, Samantha Perlstein, Yael Paz, Jakob Seidlitz, Adrian Raine, Samuel Hawes, Amy Byrd, Rebecca Waller

Abstract read
In one paragraph

Article in Journal of child psychology and psychiatry, and allied disciplines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kristin MurthaDepartment of Psychology, University of Pennsylvania, Philadelphia, PA, USA.
Samantha PerlsteinDepartment of Psychology, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-6584-0786
Yael PazDepartment of Psychology, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-1265-5923
Jakob SeidlitzDepartment of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.
Adrian RaineDepartment of Psychology, University of Pennsylvania, Philadelphia, PA, USA.
Samuel HawesDepartment of Psychology, Florida International University, Miami, FL, USA.ORCID 0000-0001-7173-1749
Amy ByrdDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-7930-6832
Rebecca WallerDepartment of Psychology, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-5069-1183

Funding

FIU-ABCD: Pathways and Mechanisms to Addiction in the Latino Youth of South FloridaU01DA041156 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI Raul Gonzalez, Angela R Laird · 2015 to 2026
$22.8M
Risky Parenting and Temperament Pathways To Callous-Unemotional Traits In Early ChildhoodR01MH125904 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Nicholas J Wagner, Rebecca Waller · 2022 to 2026
$3.9M
Neural mechanisms of reactive aggression in adolescence: Altered reactivity during threat and reinforcement conditioningK01MH119216 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BYRD, AMY L · 2019 to 2023
$845k
Leveraging Machine Learning Techniques to Elucidate Risk for Callous-Unemotional TraitsR21MH126162 · NIMH · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI WAGNER, NICHOLAS J, WALLER, REBECCA · 2022 to 2023
$450k
NIDA NIH HHS U01 DA041156NIMH NIH HHS K01 MH119216NIMH NIH HHS K01MH119216NIMH NIH HHS R01 MH125904NIMH NIH HHS R01MH125904NIMH NIH HHS R21 MH126162NIMH NIH HHS R21MH126162
6 · The paper itself

Abstract

backgroundMany studies show that both callous-unemotional (CU) traits (e.g., low empathy, lack of guilt) and cognitive difficulties increase risk for externalizing psychopathology across development. However, other work suggests that some aggression (e.g., relational, proactive) may rely on intact cognitive function, which could vary based on the presence of CU traits. Moreover, no prior research has adequately accounted for common risk factors shared by CU traits, cognitive difficulties, and externalizing problems, which confounds conclusions that can be drawn about their purported relationships. The current study addressed these knowledge gaps by leveraging rigorous propensity matching methods to isolate associations between CU traits and different dimensions of cognitive function and externalizing problems.

methodsAssociations between CU traits, cognitive functioning, and externalizing outcomes were tested within dimensional (n = 11,868) and propensity-matched group-based (n = 1,224) models using data from the Adolescent Brain Cognitive Development Study®, with rigorous statistical control for shared sociodemographic risk factors. Cross-sectional outcomes were parent-reported symptoms of conduct disorder (CD), oppositional defiant disorder (ODD), and attention deficit hyperactivity disorder (ADHD). Longitudinal outcomes were child-reported overt and relational aggression.

resultsCU traits were uniquely related to more parent-reported CD, ODD, ADHD symptoms, as well as more child-reported aggressive behaviors. Effects of cognitive difficulties were domain specific and were not consistent across dimensional and propensity matched models. There was minimal evidence for divergent associations between CU traits and externalizing outcomes as a function of cognition (i.e., no moderation).

conclusionsRigorous control for sociodemographic factors within propensity-matched models establish CU traits as a robust and unique risk factor for externalizing psychopathology, over and above difficulties with cognitive functioning.

Indexed as

AggressionAttention Deficit and Disruptive Behavior DisordersCognitive DysfunctionConduct DisorderEmpathyAdolescentChildCross-Sectional StudiesFemaleHumansMalePropensity Scoreaggressive behaviorcallous‐unemotional traitscognitive functionexternalizing disorders

Identifiers

PMID39496559
PMCPMC11812496

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.