Evidence mapPaperPMID 39497925Full record

ReviewFrontiers in cellular and infection microbiology2024

The ovarian cancer-associated microbiome contributes to the tumor's inflammatory microenvironment.

Min Zhang, Jiahang Mo, Wu Huang, Yiting Bao, Xukai Luo, Lei Yuan

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  8. Secretion of Extracellular Microvesicles Induced by a Fraction ofInternational journal of molecular sciences · 2025
    Article
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  10. Article
  11. Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Min Zhang *Department of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.
Jiahang Mo *Institute of Reproduction and Development, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.
Wu HuangDepartment of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.
Yiting BaoDepartment of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.
Xukai LuoDepartment of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.
Lei YuanDepartment of Gynecology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A growing body of research has established a correlation between tumors and persistent chronic inflammatory infiltration. As a primary instigator of inflammation, the majority of microbiomes naturally residing within our bodies engage in a mutually beneficial symbiotic relationship. Nevertheless, alterations in the microbiome's composition or breaches in the normal barrier function can disrupt the internal environment's homeostasis, potentially leading to the development and progression of various diseases, including tumors. The investigation of tumor-related microbiomes has contributed to a deeper understanding of their role in tumorigenesis. This review offers a comprehensive overview of the microbiome alterations and the associated inflammatory changes in ovarian cancer. It may aid in advancing research to elucidate the mechanisms underlying the ovarian cancer-associated microbiome, providing potential theoretical support for the future development of microbiome-targeted antitumor therapies and early screening through convenient methods.

Indexed as

InflammationMicrobiotaOvarian NeoplasmsTumor MicroenvironmentAnimalsCarcinogenesisDysbiosisFemaleHumansbacteriaimmune cellsinflammatory microenvironmentmicrobiomeovarian cancer

Identifiers

PMID39497925
PMCPMC11532186

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.