Evidence map›Paper›PMID 39498086›Full record

ArticleHeliyon2024

Metagenome mining divulges virulent and multidrug resistant

Reuben S Maghembe, Maximilian A K Magulye, Abdalah Makaranga, Gideon Nsubuga, Simon Sekyanzi, Edward A Moto, Savannah Mwesigwa, Eric Katagirya

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Reuben S MaghembeDepartment of Microbiology and Parasitology, Faculty of Medicine, St. Francis University College of Health and Allied Sciences (SFUCHAS), P. O. Box 175, Ifakara, Tanzania.
Maximilian A K MagulyeDepartment of Immunology and Molecular Biology, College of Health Sciences, Makerere University, Kampala, Uganda.
Abdalah MakarangaDepartment of Health and Biomedical Sciences, Didia Education and Health Organization (DEHO), P. O. Box 113, Shinyanga, Tanzania.
Gideon NsubugaDepartment of Immunology and Molecular Biology, College of Health Sciences, Makerere University, Kampala, Uganda.
Simon SekyanziDepartment of Medical Microbiology, College of Health Sciences, Makerere University, P. O. Box 7072, Kampala, Uganda.
Edward A MotoDepartment of Biology, College of Natural and Mathematical Sciences, University of Dodoma, Dodoma, Tanzania.
Savannah MwesigwaDepartment of Immunology and Molecular Biology, College of Health Sciences, Makerere University, Kampala, Uganda.
Eric KatagiryaDepartment of Immunology and Molecular Biology, College of Health Sciences, Makerere University, Kampala, Uganda.

Funding

Microbiology and Immunology Training for HIV and HIV-Related Research in Uganda (MITHU)D43TW010319 · FIC · CASE WESTERN RESERVE UNIVERSITY · PI BOOM, W. HENRY, JOLOBA, MOSES LUTAAKOME · 2016 to 2025
$3.1M
FIC NIH HHS D43 TW010319
6 · The paper itself

Abstract

Pediatric meningitis is a global health problem, with insufficiently known pathogens and antibiotic resistance (AMR) especially in low-resource settings. Here, we sought to uncover the virulence and AMR of pathogens associated with infant meningitis, treated with ceftriaxone, in Kampala, Uganda. In a bid to isolate

Indexed as

Central nervous system infectionCoinfectionKlebsiella michiganensis ST∗1b23MeningitisMetagenome miningMultidrug resistancePseudomonas aeruginosa ST242Virulence factors

Identifiers

PMID39498086
PMCPMC11532849

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.