Evidence map›Paper›PMID 39498304›Full record

ArticleiScience2024

Federated difference-in-differences with multiple time periods in DataSHIELD.

Manuel Huth, Carolina Alvarez Garavito, Lea Seep, Laia Cirera, Francisco Saúte, Elisa Sicuri, Jan Hasenauer

Abstract read
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Manuel HuthInstitute for Computational Biology, Helmholtz Munich - German Research Center for Environmental Health, Munich, Germany.
Carolina Alvarez GaravitoLIMES, Faculty of Mathematics and Natural Sciences, University of Bonn, Bonn, Germany.
Lea SeepLIMES, Faculty of Mathematics and Natural Sciences, University of Bonn, Bonn, Germany.
Laia CireraISGlobal, Barcelona, Spain.
Francisco SaúteCentro de Investigação em Saúde de Manhiça, Manhiça, Mozambique.
Elisa SicuriISGlobal, Barcelona, Spain.
Jan HasenauerInstitute for Computational Biology, Helmholtz Munich - German Research Center for Environmental Health, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Difference-in-differences (DID) is a key tool for causal impact evaluation but faces challenges when applied to sensitive data restricted by privacy regulations. Obtaining consent can shrink sample sizes and reduce statistical power, limiting the analysis's effectiveness. Federated learning addresses these issues by sharing aggregated statistics rather than individual data, though advanced federated DID software is limited. We developed a federated version of the Callaway and Sant'Anna difference-in-differences (CSDID), integrated into the DataSHIELD platform, adhering to stringent privacy protocols. Our approach reproduces key estimates and standard errors while preserving confidentiality. Using simulated and real-world data from a malaria intervention in Mozambique, we demonstrate that federated estimates increase sample sizes, reduce estimation uncertainty, and enable analyses when data owners cannot share treated or untreated group data. Our work contributes to facilitating the evaluation of policy interventions or treatments across centers and borders.

Indexed as

Computer scienceHealth informaticsMachine learning

Identifiers

PMID39498304
PMCPMC11532944

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.