ArticleArchives of osteoporosis2024
Prognostic nutritional index (PNI) is an independent predictor for functional outcome after hip fracture in the elderly: a prospective cohort study.
Article in Archives of osteoporosis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association of multidimensional biomarkers of immune, nutritional, inflammatory, and metabolic status with postoperative outcomes in older hip fracture patients: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- Predictive value of prognostic nutritional index for the long-term prognosis of elderly patients with fracture: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Comparative predictive performance of HALP score and prognostic nutritional index for mortality in ICU patients after hip fracture surgery.BMC geriatrics · 2026Article
- The prognostic nutritional index is an early predictive marker for surgical site infection after spinal fusion surgery: a nested case-control study.BMC surgery · 2026Article
- The association between the geriatric nutritional risk index (GNRI) and postoperative outcomes after hip fracture in older adults: a prospective cohort study.BMC geriatrics · 2026Observational
- The Utility of Baseline Prognostic Nutritional Index (PNI) and Functional Status Among Hip Fracture and Distal Femur Fracture Patients.Archives of orthopaedic and trauma surgery · 2026Article
- Comparison of the predictive value of CONUT, NLR, and PNI for 6-month and 1-year mortality in middle-aged and older adults with hip fractures: a retrospective study.Frontiers in nutrition · 2026Article
- Nutrition-related clinical laboratory indicators in perioperative management of geriatric hip fractures: a narrative review from risk stratification to precision intervention.Frontiers in nutrition · 2026Review
- Establishment and validation of a clinical prediction model for perioperative pneumonia in elderly patients with hip fractures combined with preoperative stroke.Frontiers in medicine · 2026Article
- Elevated neutrophil percentage-to-albumin ratio is associated with postoperative pneumonia in patients with hip fractures.Frontiers in medicine · 2026Article
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- Malnutrition in Older Hip Fracture Patients: Prevalence, Pathophysiology, Clinical Outcomes, and Treatment-A Systematic Review.Journal of clinical medicine · 2025Review
- Threshold effect of prognostic nutritional index on mortality in geriatric hip fracture patients.Scientific reports · 2025Article
- Prealbumin Adjusted Prognostic Nutritional Index May Predict the Postoperative Survival and Free Walking Abilities of Patients with Hip Fractures: A Multi-Center Follow-Up Study.Clinical interventions in aging · 2025Article
- Bridging nutrition and neurology: malnutrition's role in perioperative neurocognitive disorders.Frontiers in nutrition · 2025Review
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12 authors.
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Abstract
The prognostic nutritional index (PNI) is a useful tool for assessing nutritional status using serum albumin and lymphocyte count. This study indicates that a higher preoperative PNI correlates with improved mobility and health-related quality of life during the initial postoperative period in elderly patients with hip fractures. PURPOSE: To investigate the prognostic value of the prognostic nutritional index (PNI) in predicting mobility and health-related quality of life (HRQoL) in elderly hip fracture patients after surgery.
methodsWe prospectively involved patients aged 65 and above, who could walk freely before injury and underwent surgery between 2018 and 2019. Admission PNI was calculated as serum albumin (g/L) + 5 × total lymphocyte count (× 10
resultsOf 705 eligible patients, 487 completed all assessments. Patients in the higher PNI group had a significantly increased possibility of achieving unrestricted mobility at the 120-day follow-up (OR 1.69, 95% CI 1.10-2.61, P.adj = 0.017), while no significant differences were observed at other follow-ups. Additionally, patients in the higher PNI group had a significantly higher EQ-5D utility value at the 30-day follow-up (P.adj = 0.015). A linear regression model with adjusting for all confounders showed that admission PNI value was positively associated with EQ-5D utility values at 30-day, 120-day, and 1-year follow-up assessments (P.adj = 0.011, P.adj = 0.001, and P.adj = 0.030, respectively). However, this correlation was not observed at the 3-year time point (P.adj = 0.079).
conclusionThe PNI is a valuable predictor of functional outcomes in elderly patients with hip fractures following surgery.
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