Evidence map›Paper›PMID 39499630›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Deciphering the RNA-binding protein network during endosomal mRNA transport.

Senthil-Kumar Devan, Sainath Shanmugasundaram, Kira Müntjes, Johannes Postma, Sander H J Smits, Florian Altegoer, Michael Feldbrügge

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Accurate site-specific folding via conditional diffusion based on AlphaFold3.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Senthil-Kumar Devan *Department of Biology, Institute of Microbiology, Cluster of Excellence on Plant Sciences, Heinrich Heine University Düsseldorf, Düsseldorf 40204, Germany.ORCID 0000-0003-1680-1630
Sainath Shanmugasundaram *Department of Biology, Institute of Microbiology, Cluster of Excellence on Plant Sciences, Heinrich Heine University Düsseldorf, Düsseldorf 40204, Germany.ORCID 0009-0000-5773-8442
Kira MüntjesDepartment of Biology, Institute of Microbiology, Cluster of Excellence on Plant Sciences, Heinrich Heine University Düsseldorf, Düsseldorf 40204, Germany.ORCID 0000-0001-5160-6342
Johannes PostmaDepartment of Biology, Institute of Microbiology, Cluster of Excellence on Plant Sciences, Heinrich Heine University Düsseldorf, Düsseldorf 40204, Germany.ORCID 0009-0002-0565-4487
Sander H J SmitsCenter for Structural Studies, Heinrich Heine University Düsseldorf, Düsseldorf 40204, Germany.ORCID 0000-0003-0780-9251
Florian AltegoerDepartment of Biology, Institute of Microbiology, Cluster of Excellence on Plant Sciences, Heinrich Heine University Düsseldorf, Düsseldorf 40204, Germany.ORCID 0000-0002-6012-9047
Michael FeldbrüggeDepartment of Biology, Institute of Microbiology, Cluster of Excellence on Plant Sciences, Heinrich Heine University Düsseldorf, Düsseldorf 40204, Germany.ORCID 0000-0003-0046-983X

Funding

Deutsche Forschungsgemeinschaft (DFG) 417919780Deutsche Forschungsgemeinschaft (DFG) EXC-2048/1 - Project ID 39068111Deutsche Forschungsgemeinschaft (DFG) INST 208/740-1 FUGGDeutsche Forschungsgemeinschaft (DFG) INST 208/868-1 FUGGDeutsche Forschungsgemeinschaft (DFG) Project-ID 267205415 - SFB 1208 to MF (project A09)Deutsche Forschungsgemeinschaft (DFG) Project ID 458090666 - SFB1535
6 · The paper itself

Abstract

Microtubule-dependent endosomal transport is crucial for polar growth, ensuring the precise distribution of cellular cargos such as proteins and mRNAs. However, the molecular mechanism linking mRNAs to the endosomal surface remains poorly understood. Here, we present a structural analysis of the key RNA-binding protein Rrm4 from

Indexed as

EndosomesRNA, MessengerUstilagoFungal ProteinsHumansModels, MolecularProtein BindingProtein DomainsRNA-Binding ProteinsRNA TransportFungal ProteinsRNA-Binding ProteinsRNA, MessengerendosomePAM2RNA transportSLiMUstilago maydis

Identifiers

PMID39499630
PMCPMC11572963

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.