Evidence map›Paper›PMID 39499667›Full record

ReviewPlant physiology2025

Metabolic flux analysis to increase oil in seeds.

Thiya Mukherjee, Shrikaar Kambhampati, Stewart A Morley, Timothy P Durrett, Doug K Allen

Abstract readReview
In one paragraph

Review in Plant physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thiya MukherjeeDonald Danforth Plant Science Center, 975 North Warson Road, St. Louis, MO 63132, USA.ORCID 0000-0003-4053-4501
Shrikaar KambhampatiSalk Institute for Biological Studies, 10010 N Torrey Pines Rd, La Jolla, CA 92037, USA.ORCID 0000-0003-1582-0733
Stewart A MorleyDonald Danforth Plant Science Center, 975 North Warson Road, St. Louis, MO 63132, USA.ORCID 0000-0001-5340-7945
Timothy P DurrettDepartment of Biochemistry and Molecular Biophysics, Kansas State University, 1711 Claflin Rd, Manhattan, KS 66502, USA.ORCID 0000-0001-5415-9111
Doug K AllenDonald Danforth Plant Science Center, 975 North Warson Road, St. Louis, MO 63132, USA.ORCID 0000-0001-8599-8946

Funding

Department of Energy Office of Science, Office of Biological and Environmental Research DE SC0023142United Soybean Board 2020-152-0103USDA National Institute of Food and Agriculture 2021-67013-33778
6 · The paper itself

Abstract

Ensuring an adequate food supply and enough energy to sustainably support future global populations will require enhanced productivity from plants. Oilseeds can help address these needs; but the fatty acid composition of seed oils is not always optimal, and higher yields are required to meet growing demands. Quantitative approaches including metabolic flux analysis can provide insights on unexpected metabolism (i.e. when metabolism is different than in a textbook) and can be used to guide engineering efforts; however, as metabolism is context specific, it changes with tissue type, local environment, and development. This review describes recent insights from metabolic flux analysis in oilseeds and indicates engineering opportunities based on emerging topics and developing technologies that will aid quantitative understanding of metabolism and enable efforts to produce more oil. We also suggest that investigating the key regulators of fatty acid biosynthesis, such as transcription factors, and exploring metabolic signals like phytohormones in greater depth through flux analysis could open new pathways for advancing genetic engineering and breeding strategies to enhance oil crop production.

Indexed as

Metabolic Flux AnalysisPlant OilsSeedsFatty AcidsFatty AcidsPlant Oils

Identifiers

PMID39499667
PMCPMC11823122

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.