Evidence map›Paper›PMID 39501642›Full record

ArticleJournal of medicinal chemistry2024

Inhibition of Human Salivary and Pancreatic α-Amylase by Resveratrol Oligomers.

Rizliya Visvanathan, Dang Truong Le, Sushil Dhital, Topul Rali, Rohan A Davis, Gary Williamson

Abstract read
In one paragraph

Article in Journal of medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rizliya VisvanathanMolecular Nutrition Group, Department of Nutrition, Dietetics and Food, Monash University, Victorian Heart Institute, Victoria Heart Hospital, 631 Blackburn Road, Clayton, VIC 3168, Australia.ORCID 0000-0002-8788-814X
Dang Truong LeMolecular Nutrition Group, Department of Nutrition, Dietetics and Food, Monash University, Victorian Heart Institute, Victoria Heart Hospital, 631 Blackburn Road, Clayton, VIC 3168, Australia.
Sushil DhitalBioresource Processing Research Institute of Australia (BioPRIA), Department of Chemical and Biological Engineering, Monash University, Clayton, VIC 3800, Australia.ORCID 0000-0001-9405-1244
Topul RaliSchool of Natural and Physical Sciences, The University of Papua New Guinea, Port Moresby, Papua New Guinea.
Rohan A DavisInstitute for Biomedicine and Glycomics, Griffith University, Brisbane, QLD 4111, Australia.ORCID 0000-0003-4291-7573
Gary WilliamsonMolecular Nutrition Group, Department of Nutrition, Dietetics and Food, Monash University, Victorian Heart Institute, Victoria Heart Hospital, 631 Blackburn Road, Clayton, VIC 3168, Australia.ORCID 0000-0002-5624-6267

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A key strategy to mitigate postprandial hyperglycemia involves inhibiting α-amylases, which commence the starch digestion process in the gut. This study examined the inhibitory effects of resveratrol and stilbenoid tetramers, vaticanol B, (-)-hopeaphenol, and vatalbinoside A on human salivary and pancreatic α-amylases experimentally and through molecular docking studies. Vaticanol B demonstrated the most potent inhibition with IC

Indexed as

Enzyme InhibitorsMolecular Docking SimulationPancreatic alpha-AmylasesResveratrolSalivary alpha-AmylasesStilbenesalpha-AmylasesHumansKineticsStructure-Activity Relationshipalpha-AmylasesEnzyme InhibitorsPancreatic alpha-AmylasesResveratrolSalivary alpha-AmylasesStilbenes

Identifiers

PMID39501642
PMCPMC11571111

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.