Evidence map›Paper›PMID 39502732›Full record

ArticleAnnals of gastroenterological surgery2024

High risk of multiple gastric cancers in Japanese individuals with Lynch syndrome.

Nobuhiko Kanaya, Thijs A van Schaik, Hideki Aoki, Yumiko Sato, Fumitaka Taniguchi, Kunitoshi Shigeyasu, Kokichi Sugano, Kiwamu Akagi, Hideyuki Ishida, Kohji Tanakaya

Abstract read
In one paragraph

Article in Annals of gastroenterological surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nobuhiko KanayaDepartment of Surgery National Hospital Organization Iwakuni Clinical Center Yamaguchi Japan.ORCID https://orcid.org/0000-0002-0427-4426
Thijs A van SchaikDepartment of Neurosurgery Brigham and Women's Hospital, Harvard Medical School Boston Massachusetts USA.
Hideki AokiDepartment of Surgery National Hospital Organization Iwakuni Clinical Center Yamaguchi Japan.
Yumiko SatoDepartment of Pathology National Hospital Organization Iwakuni Clinical Center Yamaguchi Japan.
Fumitaka TaniguchiDepartment of Surgery National Hospital Organization Iwakuni Clinical Center Yamaguchi Japan.
Kunitoshi ShigeyasuDepartment of Surgery National Hospital Organization Iwakuni Clinical Center Yamaguchi Japan.
Kokichi SuganoDepartment of Genetic Medicine Kyoundo Hospital, SSasaki Foundation Tokyo Japan.
Kiwamu AkagiDivision of Molecular Diagnosis and Cancer Prevention Saitama Cancer Center Saitama Japan.
Hideyuki IshidaDepartment of Digestive Tract and General Surgery, Saitama Medical Center Saitama Medical University Kawagoe Japan.
Kohji TanakayaDepartment of Surgery National Hospital Organization Iwakuni Clinical Center Yamaguchi Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Lynch syndrome (LS) is a dominantly inherited syndrome characterized by an increased risk for LS associated tumors such as colorectal cancer (CRC) and gastric cancer (GC). However, the clinical benefit of surveillance for GC remains unclear while it has already been recommended for CRC. This study aimed to elucidate the clinical features of GC in Japanese individuals with LS, and the risk of developing multiple GCs to build regional-tailored surveillance programs in LS patients with GC. Methods: Data on Japanese individuals with LS were retrospectively collected from a single institution. The clinical features of GC, including the cumulative risk of multiple GCs, were analyzed. Results: Among 96 individuals with LS ( Conclusion: Due to a higher risk of developing multiple GCs, intensive surveillance might be especially recommended for Japanese individuals with LS associated initial GC.

Indexed as

cumulative riskgastric cancerJapanese individualsLynch syndromemultiple gastric cancers

Identifiers

PMID39502732
PMCPMC11533028

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.