Evidence map›Paper›PMID 39502876›Full record

ArticleFrontiers in nutrition2024

Modulation of gut microbiome in response to the combination of

Kiran Heer, Manpreet Kaur, Dwinder Sidhu, Priyankar Dey, Saumya Raychaudhuri

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kiran Heer *Molecular Biology and Microbial Physiology Division, CSIR-Institute of Microbial Technology, Chandigarh, India.
Manpreet Kaur *Molecular Biology and Microbial Physiology Division, CSIR-Institute of Microbial Technology, Chandigarh, India.
Dwinder SidhuDepartment of Biotechnology, Thapar Institute of Engineering & Technology, Patiala, Punjab, India.
Priyankar DeyDepartment of Biotechnology, Thapar Institute of Engineering & Technology, Patiala, Punjab, India.
Saumya RaychaudhuriMolecular Biology and Microbial Physiology Division, CSIR-Institute of Microbial Technology, Chandigarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The differential effects of probiotic, prebiotic, and synbiotic formulations on human health are dictated by the inter-individual gut microbial profile. The effects of probiotics such as Method: Processed fecal samples from donors having contrasting lifestyles, dietary patterns, and disease histories were mixed with 5 × 10 Result: Baseline gut microbial profiles showed significant inter-individual variations. ECN treatment alone had a limited impact on the inter-personal gut microbial diversity and abundance. Prebiotics caused a substantial enrichment in Actinobacteria, but there were differences in the responses at the order and genus levels, with enrichment shown in Conclusion: The interindividual microbiome composition strongly influences the effectiveness of personalized diet and treatment plans. The responsiveness to dietary strategies varies according to individual microbiome profiles influenced by health, diet, and lifestyle. Therefore, tailored approaches that consider individual microbiome compositions are crucial for maximizing gut health and treatment results.

Indexed as

Escherichia coli Nissle 1917interindividual variationmicrobiomeprebioticprobioticsynbiotic

Identifiers

PMID39502876
PMCPMC11534610

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.