Evidence map›Paper›PMID 39504065›Full record

ArticleBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica2024

Association of Hibiscus sabdariffa and high-intensity interval training induces reduction in adiposity and beneficial metabolic adaptations in obesity without changes in lipid metabolism.

D B O de Oliveira, M A Giordani, R A M Luvizotto, A F do Nascimento, M C Dos Santos, K C C Santos, A P Lima-Leopoldo, A S Leopoldo, M M Sugizaki

Abstract read
In one paragraph

Article in Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

D B O de OliveiraPrograma de Pós-Graduação em Educação Física, Centro de Educação Física e Esportes, Universidade Federal do Mato Grosso, Cuiabá, MT, Brasil.ORCID http://orcid.org/0000-0002-4482-0313
M A GiordaniPrograma de Pós-Graduação em Educação Física, Centro de Educação Física e Esportes, Universidade Federal do Mato Grosso, Cuiabá, MT, Brasil.ORCID http://orcid.org/0000-0003-1041-5325
R A M LuvizottoPrograma de Pós-Graduação em Ciências em Saúde (PPGCS), Universidade Federal do Mato Grosso, Campus Universitário de Sinop, Sinop, MT, Brasil.ORCID http://orcid.org/0000-0001-9548-6338
A F do NascimentoPrograma de Pós-Graduação em Ciências em Saúde (PPGCS), Universidade Federal do Mato Grosso, Campus Universitário de Sinop, Sinop, MT, Brasil.ORCID http://orcid.org/0000-0001-6118-2133
M C Dos SantosPrograma de Pós-Graduação em Ciências Fisiológicas, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Vitória, ES, Brasil.ORCID http://orcid.org/0009-0001-7891-7105
K C C SantosPrograma de Pós-Graduação em Nutrição e Saúde, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Vitória, ES, Brasil.ORCID http://orcid.org/0000-0001-8634-4127
A P Lima-LeopoldoPrograma de Pós-Graduação em Nutrição e Saúde, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Vitória, ES, Brasil.ORCID http://orcid.org/0000-0002-4049-4418
A S LeopoldoPrograma de Pós-Graduação em Ciências Fisiológicas, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Vitória, ES, Brasil.ORCID http://orcid.org/0000-0001-5999-2671
M M SugizakiPrograma de Pós-Graduação em Educação Física, Centro de Educação Física e Esportes, Universidade Federal do Mato Grosso, Cuiabá, MT, Brasil.ORCID http://orcid.org/0000-0002-4513-0883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-intensity interval training (HIIT) has stood out as a treatment for obesity, leading to adaptations of the cardiovascular system and reducing body adiposity. In addition, the search for alternative therapies for weight loss has intensified. The administration of Hibiscus sabdariffa (Hs) has been described as an efficient supplement in weight loss and in the treatment of metabolic changes associated with obesity. In this context, the objective was to investigate the effects of the association of Hs and HIIT on metabolic adaptations and lipid metabolism in obese rats. Wistars rats were subjected to obesity and subsequently randomized into 4 groups: obese (Ob), obese + HS (ObHs), obese + HIIT (ObHIIT), and obese + HS + HIIT (ObHsHIIT). For 8 weeks, ObHs and ObHsHIIT rats received Hs extract daily (150 mg/kg of body weight) and trained groups (ObHIIT and ObHsHIIT) were subjected to a HIIT program on a treadmill. Nutritional profile, glycemic curve, biochemical profile, and liver glycogen were determined. HIIT decreased caloric intake, feed efficiency, body adiposity, total body fat, and body weight gain, associated with improvements in physical performance parameters and a smaller glycemic curve and area. Hs had a hepatoprotective effect, reducing alkaline phosphatase values, but its effects were more pronounced when associated with HIIT. Therefore, the combination of treatments promoted a reduction in food consumption and body adiposity, as well as an improvement in physical performance and glycemic profile, but without changes in lipid metabolism.

Indexed as

AdiposityHibiscusHigh-Intensity Interval TrainingLipid MetabolismObesityPhysical Conditioning, AnimalPlant ExtractsRats, WistarAnimalsMaleRandom AllocationRatsPlant Extracts

Identifiers

PMID39504065
PMCPMC11540260

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.