Evidence mapPaperPMID 39504288Full record

ReviewIEEE transactions on computational biology and bioinformatics

AI-Based Computational Methods in Early Drug Discovery and Post Market Drug Assessment: A Survey.

Flora Rajaei, Cristian Minoccheri, Emily Wittrup, Richard C Wilson, Brian D Athey, Gilbert S Omenn, Kayvan Najarian

Abstract readReview
In one paragraph

Review in IEEE transactions on computational biology and bioinformatics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Flora Rajaei
Cristian Minoccheri
Emily Wittrup
Richard C Wilson
Brian D Athey
Gilbert S Omenn
Kayvan Najarian

Funding

ZINC GLUCONATE GLYCINE LOZENGES &VITAMIN C EFFECTS ON COMMON COLDM01RR000042 · NCRR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BREWER, GEORGE J · 1985 to 2007
$40.8M
Strategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI John D. Meeker · 2011 to 2026
$21.3M
Michigan Center for Translational Cancer Proteogenomics-Diversity SupplementU24CA271037 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Saravana Mohan Dhanasekaran, Alexey I Nesvizhskii · 2022 to 2026
$4.4M
NCI NIH HHS U24 CA271037NCRR NIH HHS M01 RR000042NIEHS NIH HHS P30 ES017885
6 · The paper itself

Abstract

Over the past few years, artificial intelligence (AI) has emerged as a transformative force in drug discovery and development (DDD), revolutionizing many aspects of the process. This survey provides a comprehensive review of recent advancements in AI applications within early drug discovery and post-market drug assessment. It addresses the identification and prioritization of new therapeutic targets, prediction of drug-target interaction (DTI), design of novel drug-like molecules, and assessment of the clinical efficacy of new medications. By integrating AI technologies, pharmaceutical companies can accelerate the discovery of new treatments, enhance the precision of drug development, and bring more effective therapies to market. This shift represents a significant move towards more efficient and cost-effective methodologies in the DDD landscape.

Indexed as

Artificial IntelligenceComputational BiologyDrug DiscoveryDrug DevelopmentHumans

Identifiers

PMID39504288
PMCPMC12395280

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.