Evidence map›Paper›PMID 39507011›Full record

ArticleNeurobiology of pain (Cambridge, Mass.)

The pace of biological aging significantly mediates the relationship between internalized stigma of chronic pain and chronic low back pain severity among non-hispanic black but not non-hispanic white adults.

Khalid W Freij, Fiona B A T Agbor, Kiari R Kinnie, Vinodh Srinivasasainagendra, Tammie L Quinn, Hemant K Tiwari, Robert E Sorge, Burel R Goodin, Edwin N Aroke

Abstract read
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In one paragraph

Article in Neurobiology of pain (Cambridge, Mass.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Khalid W FreijDepartment of Acute, Chronic, & Continuing Care, School of Nursing, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Fiona B A T AgborDepartment of Acute, Chronic, & Continuing Care, School of Nursing, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Kiari R KinnieDepartment of Acute, Chronic, & Continuing Care, School of Nursing, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Vinodh SrinivasasainagendraDepartment of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Tammie L QuinnDepartment of Psychology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Hemant K TiwariDepartment of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Robert E SorgeDepartment of Psychology, College of Arts and Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Burel R GoodinDepartment of Anesthesiology, School of Medicine, Washington University, St. Louis, MO 63130, USA.
Edwin N ArokeDepartment of Acute, Chronic, & Continuing Care, School of Nursing, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to determine the nature of the relationship between the internalized stigma of chronic pain (ISCP), the pace of biological aging, and racial disparities in nonspecific chronic low back pain (CLBP). We used Dunedin Pace of Aging from the Epigenome (DunedinPACE), Horvath's, Hannum's, and PhenoAge clocks to determine the pace of biological aging in adults, ages 18 to 82 years: 74 no pain, 56 low-impact pain, and 76 high-impact pain. Individuals with high-impact pain reported higher levels of ISCP and DunedinPACE compared to those with low-impact or no pain (p < 0.001). There was no significant relationship between ISCP and epigenetic age acceleration from Horvath, Hannum, and PhenoAge clocks (

Indexed as

DunedinPACEEpigenetic ageInternalized stigmaModerated mediationNonspecific chronic low back painPace of biological agingPain disparities

Identifiers

PMID39507011
PMCPMC11539503

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.