ArticleCureus2024
Correlation of Stress and Oral Inflammatory Burden in Patients With Chronic Periodontitis in a Sample Population From Bhopal: A Randomized Clinical Study.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction Chronic periodontitis is a prevalent inflammatory disease that leads to the destruction of tooth-supporting structures. Psychological stress is a potential risk factor for periodontitis, potentially exacerbating inflammation and impairing treatment outcomes. This study aims to explore the correlation between chronic stress and oral inflammatory burden, as measured by the Periodontal Inflamed Surface Area (PISA), in a sample population from Bhopal, India. Methods This randomized clinical study included 1,250 participants, divided into three groups: Group A (control, n=250), Group B (chronic periodontitis, n=500), and Group C (post-treatment chronic periodontitis, n=500). Participants underwent a comprehensive periodontal examination, including the calculation of PISA, and completed the Perceived Stress Scale-10 (PSS-10) to assess stress levels. Statistical analysis included Pearson's correlation to assess the relationship between PSS-10 scores and PISA, with comparisons among groups using analysis of variance or Kruskal-Wallis tests. Results Group B exhibited significantly higher periodontal parameters and PSS-10 scores than Group A and Group C (p<0.001 for all comparisons). Group C showed significant improvements in both periodontal parameters and PSS-10 scores following treatment (p<0.001). A positive correlation was observed between PSS-10 scores and PISA in Group B (r=0.62, p<0.001), indicating that higher perceived stress was associated with increased oral inflammation in untreated chronic periodontitis. This correlation persisted after adjusting for confounders, including age, sex, and socioeconomic status. Conclusions Chronic stress is significantly associated with increased oral inflammatory burden in patients with chronic periodontitis, suggesting that stress may act as an independent risk factor for disease progression. Periodontal therapy reduces oral inflammation and alleviates psychological distress. Integrating stress management into periodontal treatment plans may enhance patient outcomes, highlighting the importance of a holistic approach to periodontal care.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.