Evidence map›Paper›PMID 39507503›Full record

ArticleACG case reports journal2024

Tirzepatide-Associated Colonic Ischemia.

David Bayless, Jasraj Singh, Byoung Uk Park, Seth Sweetser

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Semaglutide-Induced Ischemic Colitis in A Middle-Aged Female Without Vascular Risk Factors.European journal of case reports in internal medicine · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

David BaylessDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.ORCID https://orcid.org/0009-0009-8837-1044
Jasraj SinghDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
Byoung Uk ParkDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
Seth SweetserDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN.

Funding

Mayo Clinic StARR ProgramR38HL150086 · NHLBI · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC, KARL A. NATH · 2020 to 2026
$2.5M
NHLBI NIH HHS R38 HL150086
6 · The paper itself

Abstract

The use of the glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist tirzepatide has markedly increased for the treatment of weight loss and management of diabetes mellitus. Gastrointestinal adverse effects of GLP-1/GIP agonist therapy, including nausea, vomiting, and constipation, are common. We report a case of colonic ischemia in a 62-year-old woman which developed in association with the use of tirzepatide for weight loss. This report highlights a potential risk relationship between GLP-1/GIP agonist therapy and colonic ischemia and identifies risk factors that should be considered before prescribing tirzepatide.

Indexed as

colonic ischemiaglucagon-like peptide-1 receptor agoniststirzepatide

Identifiers

PMID39507503
PMCPMC11540430

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.