Evidence map›Paper›PMID 39507807›Full record

ArticleMedical hypothesis, discovery & innovation ophthalmology journal2024

Multifocal electroretinogram changes after panretinal photocoagulation in early proliferative diabetic retinopathy.

Fathy Mohamed Abo Elftouh Elsalhy, Mahmoud Mohammed Ahmed Ali, Mahmoud Fawzy Zaky Morsy, Abdelrahman Ahmed Ali Khattab, Ezzat Nabil Abbas Ibrahim, Hazem Elbadry Mohammed Mohammed, Ramadan Mohamed Abdelrahman Elgohary, Hossam El Din Hassan El Sayed El Baz, Mohamed Sayed Taha Abouzeid

Abstract read
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In one paragraph

Article in Medical hypothesis, discovery & innovation ophthalmology journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fathy Mohamed Abo Elftouh ElsalhyDepartment of Ophthalmology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Mahmoud Mohammed Ahmed AliDepartment of Ophthalmology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Mahmoud Fawzy Zaky MorsyDepartment of Ophthalmology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Abdelrahman Ahmed Ali KhattabDepartment of Ophthalmology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Ezzat Nabil Abbas IbrahimDepartment of Ophthalmology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Hazem Elbadry Mohammed MohammedDepartment of Ophthalmology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Ramadan Mohamed Abdelrahman ElgoharyDepartment of Ophthalmology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Hossam El Din Hassan El Sayed El BazDepartment of Ophthalmology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Mohamed Sayed Taha AbouzeidDepartment of Ophthalmology, Faculty of Medicine, Beni Suef University, Beni Suef, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Panretinal photocoagulation (PRP) impacts macular function in eyes with early proliferative diabetic retinopathy (PDR). Herein, we used the multifocal electroretinogram (mfERG) to objectively investigate this concept. Methods: In this prospective interventional case series, we enrolled patients with treatment-naive early PDR, absence of clinically significant macular edema, and requirement for PRP. All participants underwent detailed ocular examinations. We measured the best-corrected distance visual acuity (BCDVA), conducted optical coherence tomography imaging to measure central macular thickness (CMT), and performed mfERG at baseline and 3 months post-PRP. Amplitude and latency of the mfERG response were evaluated within the innermost four of the five concentric rings. Results: We enrolled 29 eyes of 23 patients with a mean (standard deviation) age of 54.3 (8.8) years and male-to-female ratio of 1:1.3. The mean BCDVA was unchanged post-treatment ( Conclusions: Macular function was decreased 3 months post-PRP in patients with early PDR, as indicated by decreased amplitude of the mfERG, whereas the functional and anatomical parameters were stable. The mfERG served as an objective tool for measuring retinal function and predicting visual outcomes post-PRP in eyes with early PDR. A higher amplitude in the mfERG correlated substantially with a better visual outcome post-PRP. Further multi-center longitudinal studies with robust designs including different PDR severity levels may reveal additional objective after-effects of PRP

Indexed as

diabetic angiopathiesdiabetic retinopathyelectroretinographieslight coagulationmultifocal electroretinogramoptical coherence tomographypanretinal photocoagulationphotocoagulationproliferative diabetic retinopathyvisual acuity

Identifiers

PMID39507807
PMCPMC11537239

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.