ArticleFrontiers in nutrition2024
Independent and joint influence of depression and advanced lung cancer inflammation index on mortality among individuals with chronic kidney disease.
Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Unraveling the Impact of Serum Zinc Levels on Chronic Kidney Disease: Machine Learning and SHAP Value Interpretation.Food science & nutrition · 2026Article
- Beyond inflammation and cholesterol: atherogenic index of plasma mediates the link between hsCRP/HDL-C ratio and depression in US adults NHANES 2015-2020.Annals of general psychiatry · 2026Article
- The association between nutritional-inflammatory status and chronic kidney disease prognosis: a population-based study.Renal failure · 2025Article
- Association between chronic kidney disease and depression: evidence from the NHANES 2015-2018 and Mendelian randomization analysis.Clinical and experimental nephrology · 2025Article
- Depression mediates the association between lipid accumulation products and overactive bladder.Scientific reports · 2025Article
- The advanced lung cancer inflammation index has an L-shaped association with prognosis in American adults with metabolic dysfunction-associated fatty liver disease: a cohort study.Frontiers in nutrition · 2025Article
- Advanced lung cancer inflammation index as a diagnostic indicator of bone turnover in osteoporotic fracture patients: a non-linear analysis.Frontiers in endocrinology · 2025Article
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5 authors.
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Abstract
Background: The combined effect of depression and nutritional-inflammatory status on mortality in the chronic kidney disease (CKD) population is unclear. Methods: We prospectively analyzed 3,934 (weighted population: 22,611,423) CKD participants from the National Health and Nutrition Examination Survey (2007-2018). Depression and nutritional-inflammatory status were assessed with Patient Health Questionnaire 9 (PHQ-9) and Advanced Lung Cancer Inflammation Index (ALI), respectively. Weighted multivariate COX regression models, restricted cubic splines (RCS) models, and stratified analyses were used to investigate the association of PHQ-9 scores and ALI with all-cause mortality. Results: During a median follow-up of 5.8 years (interquartile range 3.4-8.6 years), a total of 985 patients died (25.0%). Each point increase in a patient's PHQ-9 score increased the risk of all-cause mortality by 4% (HR, 1.04; 95% CI, 1.02-1.06; Conclusion: In a nationally representative sample of US patients with CKD, coexisting depression and poorer nutrition-inflammation were associated with a significantly increased risk of all-cause mortality.
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