Evidence map›Paper›PMID 39512049›Full record

ReviewAnesthesia and pain medicine2024

Sugammadex for our little ones: a brief narrative review.

Soomin Lee, Woosuk Chung

Registry-linked trialAbstract readReview
In one paragraph

Review in Anesthesia and pain medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06962007 (A Prospective, Randomized, Double-Blind Study of the Incidence, Severity, and Risk Factors of Clenching Induced by Sugammadex During Neuromuscular Blockade Reversal), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06962007 narecruitingnot on this mapstarted 2025, after this paper: background citation

A Prospective, Randomized, Double-Blind Study of the Incidence, Severity, and Risk Factors of Clenching Induced by Sugammadex During Neuromuscular Blockade Reversal

TypeinterventionalSponsorWonkwang University HospitalRan2025 to 2026Enrolled240ConditionsNeuromuscular Blockade Reversal Agent, Perioperative Complications, Anesthesia, General, SugammadexArmsSugammadex 1 mg/kg Group, Sugammadex 2 mg/kg Group, Sugammadex 4 mg/kg Group, Pyridostigmine/Glycopyrrolate Group
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Error Traps in Pediatric Neuromuscular Block.Paediatric anaesthesia · 2026
    Review
  2. From visibility to influence.Anesthesia and pain medicine · 2026
    Article
  3. Review
  4. Article
  5. Age-Specific Pharmacology of Neuromuscular Blocking Agents: A Comprehensive Review.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Soomin LeeDepartment of Anesthesiology and Pain Medicine, Chungnam National University Hospital, Daejeon, Korea.
Woosuk ChungDepartment of Anesthesiology and Pain Medicine, Chungnam National University Hospital, Daejeon, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sugammadex, the first noncompetitive antagonist developed for the reversal of neuromuscular blockade (NMB), is one of the few drugs that has revolutionized anesthetic practice. However, the use of sugammadex for children between the ages of 2 and 17 years has only recently been approved and is currently not approved for children under the age of 2 years. Although the precision and reliability of reversal of NMB with sugammadex are of great benefit in pediatric anesthesia, several important questions remain regarding its use in our youngest patients. In this brief narrative review, we aim to provide an overview of the key considerations and potential challenges that anesthesiologists often face when using sugammadex in pediatric patients.

Indexed as

BradycardiaHypersensitivityNeostigmineNeuromuscular blocking agentsNewborn infantPediatricsSugammadex

Identifiers

PMID39512049
PMCPMC11558054

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.