Evidence map›Paper›PMID 39518369›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Takotsubo Cardiomyopathy After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for a Recurrent Colon Cancer: A Life-Threatening Complication.

Bogdan Moldovan, Iris-Iuliana Adam, Radu-Mihai Pisică, Vlad Untaru, Doly Stoica, Alexandra Șpac, Irina Modrigan, Mihai Ursu, Liliana Jupoiu, Adina Frâncu and 4 more

Abstract readCase Reports
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Bogdan MoldovanGeneral Surgery Department, 'St. Constantin' Hospital, 500299 Brasov, Romania.
Iris-Iuliana AdamGeneral Surgery Department, 'St. Constantin' Hospital, 500299 Brasov, Romania.
Radu-Mihai PisicăGeneral Surgery Department, 'St. Constantin' Hospital, 500299 Brasov, Romania.
Vlad UntaruAnesthesia and Intensive Care Unit, 'St. Constantin' Hospital, 500299 Brasov, Romania.
Doly StoicaAnesthesia and Intensive Care Unit, 'St. Constantin' Hospital, 500299 Brasov, Romania.
Alexandra ȘpacAnesthesia and Intensive Care Unit, 'St. Constantin' Hospital, 500299 Brasov, Romania.
Irina ModriganAnesthesia and Intensive Care Unit, Sanador Hospital, 011031 Bucharest, Romania.
Mihai UrsuCardiology Department, 'St. Constantin' Hospital, 500299 Brasov, Romania.
Liliana JupoiuCardiology Department, 'St. Constantin' Hospital, 500299 Brasov, Romania.
Adina FrâncuCardiology Department, 'St. Constantin' Hospital, 500299 Brasov, Romania.
Florentina PescaruOncology Department, 'St. Constantin' Hospital, 500299 Brasov, Romania.
Amir HubeishieOncology Department, Timiş County Emergency Clinical Hospital, 300723 Timișoara, Romania.
Adriana ZologPathology Department, Regina Maria Hospital, 400500 Cluj-Napoca, Romania.
Liliana VecerzanFaculty of Medicine, "Lucian Blaga" University, 550169 Sibiu, Romania.ORCID 0000-0002-5020-8825

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Takotsubo cardiomyopathy, or stress cardiomyopathy, is an acute heart failure condition with transient left ventricular (LV) motion abnormalities but no significant coronary artery obstruction. It mimics acute coronary syndrome (ACS), with symptoms like chest pain, dyspnea, and ECG changes. (2) Case Report: We present the case of a 44-year-old female with relapsed colon cancer and peritoneal carcinomatosis. After undergoing cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC), she experienced cardiac arrest from ventricular fibrillation 18 h postoperatively. Echocardiography revealed a reduced LV ejection fraction (20%) and apical akinesia, suggesting a Takotsubo Cardiomyopathy. Intensive resuscitation and inotropic support led to gradual recovery. Coronary angiography confirmed no coronary artery obstruction. (3) Discussion: This case highlights TTS as a rare but severe complication following major oncological surgeries, possibly triggered by both physical and emotional stressors. TTS should be considered in the differential diagnosis of perioperative cardiac events in cancer patients. (4) Conclusions: Prompt recognition and management of TTS in the perioperative period are crucial to improving outcomes, especially in high-risk oncological patients undergoing extensive surgeries.

Indexed as

acute heart failurecytoreductive surgery (CRS)hyperthermic intraperitoneal chemotherapy (HIPEC)Krukenberg tumorleft ventricular dysfunctionperioperative cardiac complicationsstress cardiomyopathyTakotsubo cardiomyopathyventricular fibrillation

Identifiers

PMID39518369
PMCPMC11545001

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.