Evidence map›Paper›PMID 39521989›Full record

ArticleBMC complementary medicine and therapies2024

Photo-physical characterizations and evaluation of in-vitro antioxidant, anti-inflammatory and antidiabetic potentials of green synthesized ackee (Blighia sapida) selenium nano-particles.

Omodele Ibraheem, Olubukola Helen Oyeniran, Oluwatobiloba Moses Ogundipe, Eunice Oluwabukunmi Abe, Temitope Adenike Oyedepo, Kehinde Oluseun Sodeinde, Stephen Oluwaseyi Damola, Tosin Benjamin Adeola

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In one paragraph

Article in BMC complementary medicine and therapies, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Omodele IbraheemDepartment of Biochemistry, Plants for Biotechnological Resources Research Group, Federal University Oye-Ekiti, Oye, Ekiti, Nigeria. omodele.ibraheem@fuoye.edu.ng.
Olubukola Helen OyeniranDepartment of Biochemistry, Plants for Biotechnological Resources Research Group, Federal University Oye-Ekiti, Oye, Ekiti, Nigeria.
Oluwatobiloba Moses OgundipeDepartment of Biochemistry, Plants for Biotechnological Resources Research Group, Federal University Oye-Ekiti, Oye, Ekiti, Nigeria.
Eunice Oluwabukunmi AbeDepartment of Biochemistry, Plants for Biotechnological Resources Research Group, Federal University Oye-Ekiti, Oye, Ekiti, Nigeria.
Temitope Adenike OyedepoDepartment of Biochemistry, Nutritional Biochemistry Research Group, Adeleke University, Ede, Osun State, Nigeria.
Kehinde Oluseun SodeindeDepartment of Chemistry, Materials and Nano Research Group, Federal University Oye-Ekiti, Oye, Ekiti State, Nigeria.
Stephen Oluwaseyi DamolaDepartment of Biochemistry, Nutritional Biochemistry Research Group, Adeleke University, Ede, Osun State, Nigeria.
Tosin Benjamin AdeolaDepartment of Biochemistry, Nutritional Biochemistry Research Group, Adeleke University, Ede, Osun State, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGreen synthesized nanoparticles have recently gained significant medicinal applications and oftentimes outperform their green sources. Selenium is of fundamental importance to human health, stemming from its distinctive physicochemical properties, such as antioxidant activity, inhibition of Lipid peroxidation, stabilization of membrane proteins, maintenance of membrane fluidity and modulation of cell signaling. Though reports have shown some therapeutic potential of Ackee plant parts such as antioxidant, anti-inflammatory, antimicrobial, neuroprotective, very few scientific proofs still exist in support of these effects.

methodsThis study synthesized selenium nanoparticles (Se-NPs) from crude methanolic extracts of Ackee leaves (AKL) and Ackee arils (AKA), examined the photo-physical characteristics of the Se-NPs and determined the in-vitro antioxidant, antidiabetic, and anti-inflammatory potentials of AKL, AKA, and their Se-NPs using established protocols.

resultsIn both leaves and arils Se-NPs: UV spectroscopy revealed a qualitative absorbance at 310 nm; FTIR indicated multiple vibrations around 4000 cm

conclusionEncouraging the development and utilization of AKL, AKA, and Se-NPs will provide tremendous therapeutic efficacy and bioavailability approaches towards the management of diabetes, inflammation, and other oxidative stress-related diseases.

Indexed as

Anti-Inflammatory AgentsAntioxidantsHypoglycemic AgentsPlant ExtractsSeleniumAcanthaceaeGreen Chemistry TechnologyHumansNanoparticlesPlant LeavesAnti-Inflammatory AgentsAntioxidantsHypoglycemic AgentsPlant ExtractsSeleniumAckeeAntidiabeticAnti-inflammatoryAntioxidantNanoparticlesSelenium

Identifiers

PMID39521989
PMCPMC11550549

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.