Evidence map›Paper›PMID 39523061›Full record

ReviewInternational review of neurobiology2024

GABAergic compounds for the treatment of alcohol use disorder.

Laís F Berro, James K Rowlett, Donna M Platt

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International review of neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Laís F BerroDepartment of Psychiatry and Human Behavior, Center for Innovation and Discovery in Addictions, University of Mississippi Medical Center, Jackson, MS, United States. Electronic address: lberro@umc.edu.
James K RowlettDepartment of Psychiatry and Human Behavior, Center for Innovation and Discovery in Addictions, University of Mississippi Medical Center, Jackson, MS, United States.
Donna M PlattDepartment of Psychiatry and Human Behavior, Center for Innovation and Discovery in Addictions, University of Mississippi Medical Center, Jackson, MS, United States.

Funding

ANXIOLYTIC EFFECTS AND ABUSE OF BZ RECEPTOR LIGANDSR01DA011792 · NIDA · UNIVERSITY OF MISSISSIPPI MED CTR · PI ROWLETT, JAMES K · 1998 to 2024
$7.8M
Tolerance and Physical Dependence after Chronic Benzodiazepine TreatmentR01DA043204 · NIDA · UNIVERSITY OF MISSISSIPPI MED CTR · PI JAMES K ROWLETT · 2017 to 2026
$4.3M
GABA-A receptor subtype mechanisms and the abuse-related effects of alcoholR01AA029023 · NIAAA · UNIVERSITY OF MISSISSIPPI MED CTR · PI PLATT, DONNA M · 2020 to 2024
$2.4M
Short Sleep Duration as a Predictor of Methamphetamine Intake: Role of Orexin MechanismsR01DA058666 · NIDA · UNIVERSITY OF MISSISSIPPI MED CTR · PI LAIS F BERRO · 2024 to 2026
$2.3M
Role of orexin receptors in the abuse- and sleep-related effects of methamphetamineR00DA049886 · NIDA · UNIVERSITY OF MISSISSIPPI MED CTR · PI BERRO, LAIS F · 2022 to 2024
$747k
NIAAA NIH HHS R01 AA029023NIDA NIH HHS R00 DA049886NIDA NIH HHS R01 DA011792NIDA NIH HHS R01 DA043204NIDA NIH HHS R01 DA058666
6 · The paper itself

Abstract

Decades of research have implicated the gamma-aminobutyric acid (GABA)ergic system as one of the main mediators of the behavioral effects of alcohol. Of importance, the addiction-related effects of alcohol also have been shown to be mediated in part by GABAergic systems, raising the possibility that pharmacotherapies targeting GABAergic receptors may be promising candidates for the treatment of alcohol use disorder (AUD). Alcohol modulates the activity of GAB

Indexed as

AlcoholismAnimalsGABA Agentsgamma-Aminobutyric AcidHumansReceptors, GABA-AReceptors, GABA-BGABA Agentsgamma-Aminobutyric AcidReceptors, GABA-AReceptors, GABA-BAlcoholGABAGABA(A) receptorsGABA(B) receptorsGABAergic compounds

Identifiers

PMID39523061
PMCPMC11611293

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.