Evidence map›Paper›PMID 39528530›Full record

SynthesisScientific reports2024

Prevalence of metabolic syndrome and its components according to altitude levels: a systematic review and meta-analysis.

J Pierre Zila-Velasque, Pamela Grados-Espinoza, Mabel R Challapa-Mamani, Fiorella Sánchez-Alcántara, Jamil Cedillo-Balcázar, Aziz-Delgado Cs, Enrique A Hernandez-Bustamante, Jeancarlo Tejada-Flores, Antony Piano Suárez, Josmel Pacheco-Mendoza and 1 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Cardiometabolic Risk Factors in Women Exposed to High Altitude.International journal of molecular sciences · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Link Between Metabolic Syndrome, Inflammation, and Eye Diseases.International journal of molecular sciences · 2025
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

J Pierre Zila-VelasqueRed Latinoamericana de Medicina en Altitud e Investigación (REDLAMAI), Pasco, Peru.
Pamela Grados-EspinozaRed Latinoamericana de Medicina en Altitud e Investigación (REDLAMAI), Pasco, Peru.
Mabel R Challapa-MamaniRed Latinoamericana de Medicina en Altitud e Investigación (REDLAMAI), Pasco, Peru.
Fiorella Sánchez-AlcántaraRed Latinoamericana de Medicina en Altitud e Investigación (REDLAMAI), Pasco, Peru.
Jamil Cedillo-BalcázarRed Latinoamericana de Medicina en Altitud e Investigación (REDLAMAI), Pasco, Peru.
Aziz-Delgado CsRed Latinoamericana de Medicina en Altitud e Investigación (REDLAMAI), Pasco, Peru.
Enrique A Hernandez-BustamanteRed Latinoamericana de Medicina en Altitud e Investigación (REDLAMAI), Pasco, Peru.
Jeancarlo Tejada-FloresRed Latinoamericana de Medicina en Altitud e Investigación (REDLAMAI), Pasco, Peru.
Antony Piano SuárezRed Latinoamericana de Medicina en Altitud e Investigación (REDLAMAI), Pasco, Peru.
Josmel Pacheco-MendozaDirección General de Investigación Desarrollo e Innovación, Universidad Científica del Sur, Lima, Peru.
Vicente Aleixandre Benites-ZapataUnidad para la Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola, Lima, Peru. vbeniteszapata@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic syndrome has a multifactorial origin; however, epidemiological data correspond to populations located at sea level. It has been reported that the altitude can affected the prevalence due to physiological changes. The aim of this study is to show the global prevalence of metabolic syndrome at altitude and its components. We use four databases, all studies published up to November 2023. The prevalences from studies were meta-analyzed using a random-effects model. To assess sources of heterogeneity, subgroup analyses were performed. We included 28 studies. The number of participants was 29 195. The prevalence of metabolic syndrome was 30.3% (95% CI 22.8-38.4%). According to the altitude level, at 1500-2500 was 36.5%, 2500-3500 (21.8%), and > 3500 (30.9%), also it was higher in women (35.5%) that men (26.8%). It was observed that there is an inverse relationship between higher altitude and the prevalence of metabolic syndrome. Among its components, abdominal obesity and low HDL were present in more than 40.0%, while high blood pressure, high triglycerides and impaired glucose were present in less than 30.0%. We recommend that our results be considered for future research in populations living at altitude since they have different characteristics from populations at sea level.

Indexed as

AltitudeMetabolic SyndromeFemaleHumansMalePrevalenceRisk FactorsTriglyceridesTriglyceridesAltitudeMeta-analysisMetabolic syndromePrevalencePublic health

Identifiers

PMID39528530
PMCPMC11555074

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.