Evidence map›Paper›PMID 39528607›Full record

ArticleScientific reports2024

G protein-coupled receptor 91 activations suppressed mineralization in Porphyromonas gingivalis-infected osteoblasts.

Wenqi Su, Dandan Zhang, Yujia Wang, Lang Lei, Houxuan Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Pathogenicity ofFrontiers in cellular and infection microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wenqi SuDepartment of Periodontics, Nanjing Stomatological Hospital, Affiliated Hosptital of Medical School, Institute of Stomatology, Nanjing University, 30 Zhongyang Road, Nanjing, Jiangsu, 210008, People's Republic of China.
Dandan ZhangDepartment of Periodontics, Nanjing Stomatological Hospital, Affiliated Hosptital of Medical School, Institute of Stomatology, Nanjing University, 30 Zhongyang Road, Nanjing, Jiangsu, 210008, People's Republic of China.
Yujia WangDepartment of Periodontics, Nanjing Stomatological Hospital, Affiliated Hosptital of Medical School, Institute of Stomatology, Nanjing University, 30 Zhongyang Road, Nanjing, Jiangsu, 210008, People's Republic of China.
Lang LeiDepartment of Orthodontics, Nanjing Stomatological Hospital, Affiliated Hosptital of Medical School, Institute of Stomatology, Nanjing University, Nanjing, People's Republic of China.
Houxuan LiDepartment of Periodontics, Nanjing Stomatological Hospital, Affiliated Hosptital of Medical School, Institute of Stomatology, Nanjing University, 30 Zhongyang Road, Nanjing, Jiangsu, 210008, People's Republic of China. lihouxuan3435_0@163.com.

Funding

National Natural Science Foundation of China No. 82371007Postgraduate Research & Practice Innovation Program of Jiangsu Province KYCX23_0196
6 · The paper itself

Abstract

Succinate receptor GPR91 is one of the G protein-coupled receptors (GPCRs) that interacts with various proteins to regulate diverse cellular functions such as cell morphology, apoptosis, and differentiation. In this study, we investigated whether the GPR91-mediated signaling pathway regulates mineralization in Porphyromonas gingivalis (P. gingivalis)-treated osteoblasts and to determine its potential role in osteoclast differentiation. Primary mouse osteoblasts from wild-type (WT) and GPR91 knockout (GPR91

Indexed as

Mice, KnockoutOsteoblastsPorphyromonas gingivalisReceptors, G-Protein-CoupledAnimalsBacteroidaceae InfectionsCalcification, PhysiologicCell DifferentiationCell MovementCells, CulturedMiceNF-kappa BOsteoclastsOsteogenesisRANK LigandSignal TransductionGPR91 protein, mouseNF-kappa BRANK LigandReceptors, G-Protein-CoupledGPR91MineralizationNF-κBOsteoblastsP. gingivalis

Identifiers

PMID39528607
PMCPMC11554824

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.