Evidence map›Paper›PMID 39532779›Full record

ReviewPharmaceutical research2024

Pharmacological Innovations in Space: Challenges and Future Perspectives.

Zinnet Şevval Aksoyalp, Aybala Temel, Merve Karpuz

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pharmaceutical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Deep space environment empowering drug design and development.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zinnet Şevval Aksoyalp *Department of Pharmacology, Faculty of Pharmacy, Izmir Katip Celebi University, 35620, Izmir, Türkiye.ORCID http://orcid.org/0000-0002-7822-3154
Aybala Temel *Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Izmir Katip Celebi University, 35620, Izmir, Türkiye.ORCID http://orcid.org/0000-0003-1549-7219
Merve Karpuz *Department of Radiopharmacy, Faculty of Pharmacy, Izmir Katip Celebi University, 35620, Izmir, Türkiye. merve.karpuz@ikcu.edu.tr.ORCID http://orcid.org/0000-0001-6681-2448

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSince the first human experience in space, the interest in space research and medicine to explore universe is growing day by day. The extreme space conditions mainly radiation and microgravity effects on human physiology, antimicrobial susceptibility, and efficacy, safety, and stability of drugs. Therefore, the aim of this review is to address the impact of extreme space conditions, mainly microgravity and radiation, on human physiology and highlights the need for future approaches by evaluating the effectiveness of strategies to prevent or mitigate health problems.

methodsPublished papers and NASA technical documents were searched in Pubmed and Google Scholar databases using the keywords ''antimicrobial susceptibility or drug resistance or drug stability or innovations or pharmacokinetic or pharmacodynamics'' and ''radiation or microgravity or space environments or space medicine or space pharmacy'' to prepare this review.

resultsIn this review, the challenges regarding physiological effects and drug-related problems are examined through the evaluation of extreme conditions in space. Medications used in spaceflight are summarized, and the role of pharmacists specializing in space medicine is briefly explained. Last but not least, to overcome the aforementioned issues, novel approaches have been addressed, such as personalised treatments, development of space-resistant formulations and various microbial applications.

conclusionsFurther research in the space medicine is required to facilitate the safe and healthy travel of humans to the Moon, Mars and other extraterrestrial destinations. One bear in mind that space research will contribute not only to the exploration of the universe, but also to the advancement of health and technological discoveries on Earth.

Indexed as

Space FlightWeightlessnessAerospace MedicineAnimalsHumansPharmaceutical PreparationsPharmacistsPharmaceutical PreparationsAntimicrobialAstropharmacyDrug resistanceDrug stabilitiesInnovationMicrogravityRadiationSpace medicine

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.