Evidence map›Paper›PMID 39533396›Full record

ArticleJournal of nanobiotechnology2024

A novel multifunctional nanocomposite hydrogel orchestrates the macrophage reprogramming-osteogenesis crosstalk to boost bone defect repair.

Ying Wang, Yedan Chen, Tao Zhou, Jingze Li, Na Zhang, Na Liu, Pinghui Zhou, Yingji Mao

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  15. Tri-Functional MgTA@MnOInternational journal of nanomedicine · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ying Wang *Department of Orthopedics and Department of Plastic Surgery, The First Affiliated Hospital of Bengbu Medical University, Bengbu, 233004, China.
Yedan Chen *Department of Orthopedics and Department of Plastic Surgery, The First Affiliated Hospital of Bengbu Medical University, Bengbu, 233004, China.
Tao Zhou *Department of Orthopedics and Department of Plastic Surgery, The First Affiliated Hospital of Bengbu Medical University, Bengbu, 233004, China.
Jingze LiDepartment of Orthopedics and Department of Plastic Surgery, The First Affiliated Hospital of Bengbu Medical University, Bengbu, 233004, China.
Na ZhangSchool of Life Sciences, Bengbu Medical University, Bengbu, 233030, China.
Na LiuSchool of Life Sciences, Bengbu Medical University, Bengbu, 233030, China.
Pinghui ZhouDepartment of Orthopedics and Department of Plastic Surgery, The First Affiliated Hospital of Bengbu Medical University, Bengbu, 233004, China. zphdoctor@126.com.
Yingji MaoDepartment of Orthopedics and Department of Plastic Surgery, The First Affiliated Hospital of Bengbu Medical University, Bengbu, 233004, China. myj123@bbmu.edu.cn.

Funding

Anhui Provincial Clinical Medical Research Transformation Project 202304295107020077Anhui Provincial Natural Science Foundation 2308085MH262Distinguished Young Scholars of First Affiliated Hospital of Bengbu Medical University 2021byyfyjq01Domestic Visiting and Training Program for Outstanding Young Backbone Teachers in High Schools gxgnfx2022036Natural Science Research Project of the Anhui Educational Committee 2022AH020086Natural Science Research Project of the Anhui Educational Committee 2023AH051939
6 · The paper itself

Abstract

Repairing bone defects is a complex cascade reaction process, as immune system regulation, vascular growth, and osteogenic differentiation are essential. Thus, developing a tissue-engineered biomaterial that caters to the complex healing process of bone regeneration remains a major clinical challenge. In the study, Ca

Indexed as

Bone RegenerationGraphiteHydrogelsMacrophagesNanocompositesOsteogenesisAnimalsBiocompatible MaterialsBone and BonesCalciumCell DifferentiationCellular ReprogrammingGelatinMaleMethacrylatesMiceBiocompatible MaterialsCalciumGelatingraphene oxideGraphiteHydrogelsMethacrylatesTanninsImmunoregulationMacrophage reprogrammingNanocomposite hydrogelOsteogenesis

Identifiers

PMID39533396
PMCPMC11558876

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.