ArticleMagnetic resonance in medicine2025
Spectrally selective and interleaved water imaging and fat imaging (siWIFI).
Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Fat-suppressed quantitative ultrashort echo time magnetization transfer (UTE-MT) imaging of the knee joint.Magma (New York, N.Y.) · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
Abstract
purposeTo develop a novel imaging sequence that independently acquires water and fat images while being inherently insensitive to motion.
methodsThe new sequence, termed spectrally selective and interleaved water imaging and fat imaging (siWIFI), uses a narrow bandwidth RF pulse for selective excitation of water and fat separately. The interleaved acquisition method ensures that the obtained water and fat images are inherently coregistered. A radial sampling strategy further reduces motion-induced artifacts. Phantoms with lipid concentrations ranging from 0% to 50% were scanned to measure fat fraction. Moreover, healthy volunteers were scanned to assess the in vivo feasibility of fat fraction measurement at the hip, knee, and liver. In vivo fat fraction measurements were compared with those from vendor-provided iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL) scans. Furthermore, a magnetization transfer (MT) preparation module was incorporated to demonstrate the feasibility of simultaneous measurement of fat fraction and MT ratio utilizing the siWIFI framework.
resultsThe phantom fat fractions measured by siWIFI showed excellent correlation with lipid concentrations (R
conclusionThe proposed siWIFI sequence allows selective water-fat imaging and quantification with reduced motion artifacts.
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