ArticleKidney international reports2024
IMPACT CKD: Holistic Disease Model Projecting 10-Year Population Burdens.
Article in Kidney international reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Recommendations of the Brazilian Society of Nephrology for sustainable nephrology in Brazil.Jornal brasileiro de nefrologiaGuideline
- Modelled CKD Benefits of Broad Sodium-Glucose Cotransporter-2 Inhibitor Eligibility in the UK.Kidney international reports · 2026Article
- Forecasting the Multidimensional Burdens of Hospital Admissions in LRTIs and COPD: Projections of Healthcare Expenditures, Resource Utilization, and Socioeconomic and Environmental Outcomes for Switzerland.Infectious diseases and therapy · 2026Article
- Deciding between conservative kidney management and dialysis in older people with kidney failure: a narrative review.Clinical kidney journal · 2026Review
- The Increasing Value of Environmental Sustainability Assessments in Healthcare Policy and Technology Evaluation.Applied health economics and health policy · 2026Article
- System Preparedness for Rising Kidney Replacement Therapy Demand: Late-Stage CKD Drives Costs, Healthcare Resource Utilisation and Environmental Impact in Switzerland.Advances in therapy · 2026Article
- PaCE CKD: A Multinational Survey of Financial Burden and Work Productivity in Patients with Chronic Kidney Disease and Caregivers.Advances in therapy · 2026Article
- IL‑1 receptor antagonism attenuates renal fibrosis via RNF182‑driven MFN2 destabilization and mitochondrial dysfunction.Cell death discovery · 2025Article
- Healthcare workload associated with transition onto kidney replacement therapy: a retrospective cohort study.BMC nephrology · 2025Article
- Impact of Improved Diagnosis and Treatment on Holistic CKD Burden.Kidney international reports · 2025Article
- Response to the Letter to the Editor Entitled "IMPACT CKD - All Roads Must Not Lead to Dialysis".Kidney international reports · 2025Article
- IMPACT CKD - All Roads Must not Lead to Dialysis.Kidney international reports · 2025Article
- Holistic Impact of CKD: A Clinical, Economic, and Environmental Analysis by IMPACT CKD.Kidney international reports · 2025Article
- Reducing CKD burden in Europe: first make the elephant apparent!Clinical kidney journal · 2025Article
- Cost-effectiveness of population-based screening for chronic kidney disease among the general population and adults with diabetes in China: a modelling study.The Lancet regional health. Western Pacific · 2025Article
- Periodontitis in Patients Receiving Haemodialysis: A Scoping Review.International journal of dentistry · 2025Review
- EPI-CKD Brazil: point-of-care screening for chronic kidney disease during World Kidney Day.Jornal brasileiro de nefrologiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: The significant burden of chronic kidney disease (CKD) is not recognized as a global public health priority, although policies aimed at delaying progression to later stages are required. Therefore, there is need for a holistic disease model to inform decision making that accounts for the multidimensional impact of CKD, and the interrelated factors that modulate progression. Methods: IMPACT CKD is a microsimulation model that simulates CKD progression and incorporates the effect of clinical events and comorbidities. CKD status is assigned using estimated glomerular filtration rate (eGFR) and albuminuria levels, and CKD progression is predicted by an annual eGFR decline rate. The model projects clinical, health care resource use, economic, patient, societal, and environmental burdens from 2022 to 2032. During development, face, technical, and external validity were evaluated, with calibration conducted to population data. Further, cross-validation was conducted against 2 published models. The United Kingdom (UK) was selected as the case study for validation. Results: A 7.7% increase in the CKD population by 2032 was predicted, with increasing numbers of patients with CKD stage 3 to 5 (21.7%), dialysis (75.3%), and transplantation (58.7%). The increase of patients on renal replacement therapy (RRT) results in an increase of 75% across freshwater use, fossil fuel depletion, and CO Conclusion: The IMPACT CKD model is a robust simulation that delivers validated forecasts of the holistic CKD burden, which can support evaluation of diverse health policies and treatment strategies.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.