Evidence map›Paper›PMID 39537428›Full record

SynthesisPhytotherapy research : PTR2025

Perspectives, Experiences, and Practices of Healthcare Professionals and Patients Towards Herb-Drug Interaction: A Systematic Review of Qualitative Studies.

Chen Shen, Zhi-Ying Ren, Hui-Di Lan, Ling-Yao Kong, Ming Yang, You-Zhu Su, Xiao-Lei Yue, Zu-Lin Wan, Li-Xue Xiao, Pi-Pi Chen and 4 more

Abstract readSystematic Review
In one paragraph

Synthesis in Phytotherapy research : PTR, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Chen ShenCentre for Evidence Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.ORCID https://orcid.org/0000-0002-5439-7133
Zhi-Ying RenBeijing University of Chinese Medicine, Beijing, China.
Hui-Di LanRuikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, China.
Ling-Yao KongCentre for Evidence Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Ming YangBeijing University of Chinese Medicine Third Affiliated Hospital, Beijing, China.
You-Zhu SuCentre for Evidence Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Xiao-Lei YueGuangxi University of Chinese Medicine, Nanning, China.
Zu-Lin WanGuang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Li-Xue XiaoBeijing University of Chinese Medicine, Beijing, China.
Pi-Pi ChenBeijing University of Chinese Medicine, Beijing, China.
Xun LiCentre for Evidence Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Xian ZhouNICM Health Research Institute, Western Sydney University, Sydney, Australia.ORCID https://orcid.org/0000-0001-8766-8158
Nicola RobinsonCentre for Evidence Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Jian-Ping LiuCentre for Evidence Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.

Funding

Guest Professor of Beijing University of Chinese Medicine 20210017High-Level Talent Research Start-up Fund 90011451310039Research Support Program Fellowship, Western Sydney University
6 · The paper itself

Abstract

The aim of the study was to understand healthcare professionals, pharmacists, and patients perspectives and experiences on clinical practice of herb-drug interactions (HDIs). A systematic review of qualitative studies was conduct. 10 electronic databases were searched from inception through September 2023. Qualitative studies, mixed-method studies, and unstructured or semi-structured cross-sectional surveys focused on healthcare professionals, pharmacists and patients' perspectives, attitudes, clinical practice behaviors, and information needs regarding HDI were included. Thematic synthesis employed Nvivo 12 software. Of 6655 studies identified, 1267 full-text articles were retrieved. Of these, 18 studies conducted in 11 countries/regions were eligible for inclusion, involving 1273 patients, 302 healthcare professionals, and 230 pharmacists. Five over-arching explanatory themes were identified: perspectives, attitudes, practices, experiences, expectations, and information needs. Complementary and alternative (CAM) physicians, pharmacists, and general practitioners were considered by patients to possess the ability or responsibility to assess potential HDIs. Pharmacists yet encountered difficulties due to conflicting information sources and inadequate training. Healthcare professionals, including pharmacists, usually only assessed HDIs when they were deemed to cause serious adverse effects. Regarding expectations and information needs, patients were particularly concerned about the risk of adverse HDIs, the severity of HDIs, and the appropriate intervals between drug doses. They would like to receive relevant HDI alerts. Results suggest that government, policy makers, healthcare professionals, and the education system should give attention to HDIs and improve health professional-patient communication. Further research should also be conducted on the understanding and practices of CAM practitioners in China. Trial Registration: CRD42022324777 (https://www.crd.york.ac.uk/PROSPERO/#recordDetails).

Indexed as

Attitude of Health PersonnelHealth Knowledge, Attitudes, PracticeHealth PersonnelHerb-Drug InteractionsPatientsHumansPharmacistsQualitative Researchcomplementary and alternative practitionergeneral practitionerherb–drug interactionmixed‐method studypatient knowledgeperspectivepharmacistpracticequalitative studysystematic review

Identifiers

PMID39537428
PMCPMC11745149

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.