ArticleFrontiers in medicine2024
The causal role of gastroesophageal reflux disease in endometriosis: a bidirectional Mendelian randomization study.
Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Comorbidity analysis and clustering of endometriosis patients using electronic health records.Cell reports. Medicine · 2025Article
- Commentary: The causal role of gastroesophageal reflux disease in endometriosis: a bidirectional Mendelian randomization study.Frontiers in medicine · 2025Article
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4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Observational studies have reported an association between gastroesophageal reflux disease (GERD) and endometriosis. We conducted a two-sample and bidirectional Mendelian randomization analysis to determine whether those associations are causal. Two-sample and bidirectional MR analyses were performed using summary statistics from the European Individual Genome-Wide Association Study (GWAS). The inverse variance weighting (IVW) method is used as the main analysis method to evaluate causality. Sensitivity analyses were performed to assess heterogeneity, horizontal versatility, and stability. The results showed no significant causal association between GERD in women with endometriosis in the UK Bank database [ratio (OR) ≈ 0, 95% adjusted interval (CI) 1.0007∼1.0044,
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