ArticlePloS one2024
Added sugars and risk of osteoarthritis in adults: A case-control study based on National Health and Nutrition Examination Survey 2007-2018.
Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Methylation of PRDX3 Expression Alleviate Ferroptosis and Oxidative Stress in Patients with Osteoarthritis Cartilage Injury.Archives of rheumatology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAdded sugars have been associated with a variety of adverse health consequences, but their relationship with osteoarthritis is unclear. This study aimed to demonstrate the association between added sugars and osteoarthritis.
methodsWe used the National Health and Nutrition Examination Survey (NHANES) database from 2007 to 2018 to explore the association between added sugars and osteoarthritis.
resultsIn our study, 2,746 adults were included. The average age of the chosen participants was 43.77 years, with 52.33% males and 47.67% females. There were 2,152 in the osteoarthritis group and 594 in the non-osteoarthritis group, weighted to represent 11,854,966 participants. In the fully adjusted multivariable model 3, added sugars were found as a risk factor for osteoarthritis (OR = 1.01; 95% CI 1.00 to 1.01), with populations in the fourth quartile having a greater prevalence of osteoarthritis (OR = 1.40; 95% CI 1.09 to 1.81). When added sugars were treated as a continuous variable in subgroup analysis, the results indicated that never consumed alcohol (OR = 1.02; 95% CI 1.01 to 1.04) and no history of diabetes (OR = 1.02; 95% CI 1.01 to 1.04)were more Likely tend to osteoarthritis. When added sugars were treated as a categorical variable in subgroup analysis, the results indicated that compared to the first group, in the fourth quartile population, females (OR = 1.44; 95% CI 1.02 to 2.02), low BMI (OR = 1.88; 95% CI 1.06 to 3.33), never smoking (OR = 1.55; 95% CI 1.05 to 2.30), never consumed alcohol (OR = 3.31; 95% CI 1.42 to 7.74), no history of hypertension (OR = 1.51; 95% CI 1.00 to 2.27), and no history of diabetes (OR = 1.44; 95% CI 1.11 to 1.87) were more likely tend to osteoarthritis.
conclusionAdded sugars are a risk factor for osteoarthritis, especially in females, low BMI, never smoking, never consumed alcohol, no history of hypertension, and no history of diabetes.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.