Evidence map›Paper›PMID 39546040›Full record

Trial reportEuropean journal of nutrition2024

Effects of long-term almond consumption on markers for vascular function and cardiometabolic risk in men and women with prediabetes: results of a randomized, controlled cross-over trial.

Marco A Chavez-Alfaro, Ronald P Mensink, Elske Gravesteijn, Peter J Joris, Jogchum Plat

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03419702 (Effects of Almond Consumption on Chronic Glucose Regulation, Vascular Function and Cognitive Performance), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03419702 nacompletednot on this map

Effects of Almond Consumption on Chronic Glucose Regulation, Vascular Function and Cognitive Performance: The AL-INCLUSIVE Trial

TypeinterventionalSponsorMaastricht University Medical CenterRan2018 to 2021Enrolled43ConditionsPreDiabetes, Impaired Glucose Tolerance, Impaired Fasting Glucose, Overweight and ObesityArmsAlmonds
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marco A Chavez-AlfaroDepartment of Nutrition and Movement Sciences, Research Institute of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, The Netherlands.ORCID https://orcid.org/0009-0002-1751-2670
Ronald P MensinkDepartment of Nutrition and Movement Sciences, Research Institute of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, The Netherlands.ORCID https://orcid.org/0000-0002-8908-3580
Elske GravesteijnDepartment of Nutrition and Movement Sciences, Research Institute of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, The Netherlands.ORCID https://orcid.org/0000-0003-0967-3618
Peter J JorisDepartment of Nutrition and Movement Sciences, Research Institute of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, The Netherlands.ORCID https://orcid.org/0000-0001-6852-5776
Jogchum PlatDepartment of Nutrition and Movement Sciences, Research Institute of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, The Netherlands. j.plat@maastrichtuniversity.nl.ORCID https://orcid.org/0000-0002-1570-9608

Funding

NUTRIM School of Nutrition and Translational Research in Metabolism NUTRIM School of Nutrition and Translational Research in Metabolism
6 · The paper itself

Abstract

purposeThe aim of this study was to investigate the long-term effects of almond consumption on peripheral vascular function, ambulant blood pressure profiles (ABP), and serum/plasma markers reflecting endothelial dysfunction and inflammation in participants with overweight/obesity and prediabetes.

methodsThirty-four participants completed this single-blinded, randomized, cross-over trial with 5-month intervention and control periods, separated by a 2-month wash-out. During the intervention period, participants consumed 50 g of whole almonds daily. At the end of each intervention period, peripheral vascular function was assessed by measuring the carotid-to-femoral and carotid-to-radial pulse wave velocities (PWV

resultsAlmond consumption did not significantly affect arterial stiffness (PWV

conclusionAlmond consumption did not affect arterial stiffness, retinal microvasculature calibers, or serum and plasma markers for endothelial dysfunction and inflammation in participants with prediabetics, while BP and BP variability were improved. CLINICAL

trial registrationThis clinical trial was registered in February 2018 as NCT03419702.

Indexed as

BiomarkersBlood PressureCross-Over StudiesPrediabetic StatePrunus dulcisAdultCardiometabolic Risk FactorsCardiovascular DiseasesDietEndothelium, VascularFemaleHumansMaleMiddle AgedPulse Wave AnalysisSingle-Blind MethodBiomarkersVascular Cell Adhesion Molecule-124-hour blood pressureAlmondsArterial stiffnessPrediabetesRetinal microvasculature

Identifiers

PMID39546040

What Socratic holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.