Evidence map›Paper›PMID 39550361›Full record

ArticleTranslational psychiatry2024

Association of polygenic liabilities for schizophrenia and bipolar disorder with educational attainment and cognitive aging.

Chi-Shin Wu, Chia-Lin Hsu, Mei-Chen Lin, Mei-Hsin Su, Yen-Feng Lin, Chia-Yen Chen, Po-Chang Hsiao, Yi-Jiun Pan, Pei-Chun Chen, Yen-Tsung Huang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chi-Shin WuNational Center for Geriatrics and Welfare Research, National Health Research Institutes, Zhunan, Taiwan.
Chia-Lin HsuCollege of Public Health, China Medical University, Taichung, Taiwan.
Mei-Chen LinNational Center for Geriatrics and Welfare Research, National Health Research Institutes, Zhunan, Taiwan.
Mei-Hsin SuCollege of Public Health, China Medical University, Taichung, Taiwan.ORCID 0000-0002-7198-4874
Yen-Feng LinCenter for Neuropsychiatric Research, National Health Research Institutes, Miaoli, Taiwan.
Chia-Yen ChenBiogen, Cambridge, MA, USA.ORCID 0000-0001-9548-5597
Po-Chang HsiaoCollege of Public Health, National Taiwan University, Taipei, Taiwan.
Yi-Jiun PanSchool of Medicine, College of Medicine, China Medical University, Taichung, Taiwan.
Pei-Chun ChenNational Center for Geriatrics and Welfare Research, National Health Research Institutes, Zhunan, Taiwan.
Yen-Tsung HuangInstitute of Statistical Science, Academia Sinica, Taipei, Taiwan.
Shi-Heng WangNational Center for Geriatrics and Welfare Research, National Health Research Institutes, Zhunan, Taiwan. shwang@nhri.edu.tw.ORCID 0000-0002-8466-2698

Funding

National Health Research Institutes (NHRI) CG-112-GP-10, CG-113-GP-10, NHRI-EX109-10931PI, NHRI-EX110-10931PI, NHRI-EX111-10931PI
6 · The paper itself

Abstract

To elucidate the specific and shared genetic background of schizophrenia (SCZ) and bipolar disorder (BPD), this study explored the association of polygenic liabilities for SCZ and BPD with educational attainment and cognitive aging. Among 106,806 unrelated community participants from the Taiwan Biobank, we calculated the polygenic risk score (PRS) for SCZ (PRS

Indexed as

Bipolar DisorderCognitive AgingEducational StatusMultifactorial InheritanceSchizophreniaAgedFemaleGenetic Predisposition to DiseaseHumansMaleMental Status and Dementia TestsMiddle AgedTaiwan

Identifiers

PMID39550361
PMCPMC11569198

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.