Evidence map›Paper›PMID 39551976›Full record

ArticleThe European journal of neuroscience2024

Loss of neuropeptide signalling alters temporal expression of mouse suprachiasmatic neuronal state and excitability.

Sven Wegner, Mino D C Belle, Pi-Shan Chang, Alun T L Hughes, Alexandra E Conibear, Charlotte Muir, Rayna E Samuels, Hugh D Piggins

Erratum issuedAbstract read
In one paragraph

Article in The European journal of neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Neuropeptidergic systems in psychiatric disorders.Frontiers in endocrinology · 2025
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Sven WegnerFaculty of Biology, Medicine, and Health, University of Manchester, Manchester, UK.
Mino D C BelleFaculty of Biology, Medicine, and Health, University of Manchester, Manchester, UK.
Pi-Shan ChangSchool of Physiology, Pharmacology, and Neuroscience, University of Bristol, Bristol, UK.
Alun T L HughesFaculty of Biology, Medicine, and Health, University of Manchester, Manchester, UK.
Alexandra E ConibearSchool of Physiology, Pharmacology, and Neuroscience, University of Bristol, Bristol, UK.
Charlotte MuirSchool of Physiology, Pharmacology, and Neuroscience, University of Bristol, Bristol, UK.
Rayna E SamuelsFaculty of Biology, Medicine, and Health, University of Manchester, Manchester, UK.
Hugh D PigginsFaculty of Biology, Medicine, and Health, University of Manchester, Manchester, UK.ORCID 0000-0003-2555-9858

Funding

Biotechnology and Biological Sciences Research Council BB/L007665Biotechnology and Biological Sciences Research Council M02239XBiotechnology and Biological Sciences Research Council R019223Biotechnology and Biological Sciences Research Council T008741Wellcome TrustWellcome Trust WT092319MA
6 · The paper itself

Abstract

Individual neurons of the hypothalamic suprachiasmatic nuclei (SCN) contain an intracellular molecular clock that drives these neurons to exhibit day-night variation in excitability. The neuropeptide vasoactive intestinal polypeptide (VIP) and its cognate receptor, VPAC

Indexed as

Receptors, Vasoactive Intestinal Peptide, Type IISuprachiasmatic Nucleus NeuronsAction PotentialsAnimalsCircadian RhythmMaleMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicNeuronsSignal TransductionSuprachiasmatic NucleusVasoactive Intestinal PeptideReceptors, Vasoactive Intestinal Peptide, Type IIVasoactive Intestinal PeptideVipr2 protein, mouseAMPAcircadiangatingneurophysiologySCNsodium currentvasoactive intestinal polypeptideVPAC2 receptor

Identifiers

PMID39551976
PMCPMC11612845

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.