Evidence map›Paper›PMID 39552201›Full record

ReviewDevelopmental medicine and child neurology2025

Informed consent in assisted reproductive technology: Implications for pediatric clinicians.

Mary E Graham, Shannon Blee, Rebecca D Pentz, Emily Roebuck, Alexander H Hoon, Mara Black

Abstract readReview
In one paragraph

Review in Developmental medicine and child neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mary E GrahamWake Forest University School of Medicine, Winston-Salem, NC, USA.ORCID 0009-0001-1904-7728
Shannon BleeCreighton University School of Medicine, Omaha, NE, USA.
Rebecca D PentzWinship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA.
Emily RoebuckWake Forest University School of Medicine, Winston-Salem, NC, USA.
Alexander H HoonDepartment of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Mara BlackDepartment of Gynecology and Obstetrics, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.

Funding

Postdoctoral Medical Genetics Training GrantT32GM007471 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI TAO WANG · 1985 to 2026
$8.0M
NIGMS NIH HHS T32 GM007471
6 · The paper itself

Abstract

After conceiving through assisted reproductive technologies (ART), parents may present to their pediatrician with concerns related to their child's neurodevelopment, including whether their child's health may be related to their use of ART. Pediatricians may be unfamiliar with the ART process and what the families endured up to this point, resulting in difficulty counseling parents through these discussions. Before presentation to the pediatrician, parents have undergone extensive evaluation with reproductive endocrinologists. During counseling, the reproductive endocrinologist provides information on maternal and childhood risks associated with ART. However, in this rapidly evolving field, providing comprehensive, patient-centered, informed consent is increasingly complex and counseling patients properly can be challenging. When parents have gone through the proper informed consent process, and when the pediatrician has an understanding of what this process entails, care of the child can be optimized. In this review, we discuss the complexities of the prenatal informed consent process that parents navigate before presenting to pediatricians. We emphasize the importance of these discussions and highlight ethical principles, as well as emotional, medical, legal, and financial stressors that parents face during ART, with the belief that this understanding will improve the care that pediatricians subsequently provide.

Indexed as

Informed ConsentPediatricsReproductive Techniques, AssistedChildFemaleHumansParents

Identifiers

PMID39552201
PMCPMC12696750

What Socratic holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.