Evidence map›Paper›PMID 39552990›Full record

ReviewCureus2024

Nanoparticle-Based Therapies for Cardiovascular Diseases: A Literature Review of Recent Advances and Clinical Potential.

Gaurav Jha, Ritika B Sharma, Sruthi Sridhar, Disha Hayagreev, Tanya Sinha, Harsimran Kaur, Adrija Das, Reddy Lahari Bollineni

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gaurav JhaTrauma and Orthopaedics, Leicester Royal Infirmary, Leicester, GBR.
Ritika B SharmaGeriatrics, Pinderfields General Hospital, MidYorkshire, GBR.
Sruthi SridharEmergency Department, Croydon Health Services NHS Trust, London, GBR.
Disha HayagreevEmergency Department, Basingstoke and North Hampshire Hospital, Basingstoke, GBR.
Tanya SinhaEmergency Medicine, South Tyneside and Sunderland NHS Foundation Trust, South Sheilds, GBR.
Harsimran KaurAccident and Emergency, Ealing Hospital, Southall, GBR.
Adrija DasMedicine, Newcastle University, Newcastle, GBR.
Reddy Lahari BollineniInternal Medicine, Royal Stoke Hospital, Stoke-on-Trent, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases (CVDs) present a significant global health burden and remain the leading cause of morbidity and mortality worldwide. Conventional pharmacological therapies have yielded limited success in addressing the underlying pathophysiology of these diseases, leading to the exploration of novel therapeutic approaches. Nanotechnology is transforming cardiovascular disease management by enabling the engineering of materials at the atomic and molecular levels. This has led to the development of advanced diagnostic tools with unparalleled accuracy and sensitivity in detecting these diseases. By enabling targeted drug delivery, enhancing imaging techniques, and facilitating personalized therapies, nanotechnology promises significant advancements in the diagnosis, treatment, and prevention of cardiovascular diseases. This narrative review provides a comprehensive outlook on the recent advancements in nanoparticle-based therapies for cardiovascular diseases. We delve into the diverse applications of various nanoparticle types, exploring their potential to surpass the limitations of conventional treatments and improve clinical outcomes. Additionally, we critically examine the challenges and future directions of this rapidly evolving field, emphasizing the need for rigorous clinical evaluation.

Indexed as

cardiovascular diseasescardiovascular interventionnanoparticlesnew drug delivery systemsnovel treatmenttargeted therapytherapeutic interventions

Identifiers

PMID39552990
PMCPMC11569831

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.