Evidence map›Paper›PMID 39553581›Full record

ArticleHeliyon2024

Existence and distribution of the microbiome in tumour tissues of children with hepatoblastoma.

Jinghua Cui, Xiaoran Li, Qun Zhang, Bing Du, Zanbo Ding, Chao Yan, Guanhua Xue, Lin Gan, Junxia Feng, Zheng Fan and 10 more

Abstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. The role of theFrontiers in microbiology · 2026
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Jinghua CuiCapital Institute of Pediatrics, Beijing, 100020, China.
Xiaoran LiPostgraduate Base of the PLA Rocket Force Medical Center, Jinzhou Medical University, Jinzhou, 121001, Liaoning Province, China.
Qun ZhangBeijing Ditan Hospital, Capital Medical University, Beijing, 100015, China.
Bing DuCapital Institute of Pediatrics, Beijing, 100020, China.
Zanbo DingCapital Institute of Pediatrics, Beijing, 100020, China.
Chao YanCapital Institute of Pediatrics, Beijing, 100020, China.
Guanhua XueCapital Institute of Pediatrics, Beijing, 100020, China.
Lin GanCapital Institute of Pediatrics, Beijing, 100020, China.
Junxia FengCapital Institute of Pediatrics, Beijing, 100020, China.
Zheng FanCapital Institute of Pediatrics, Beijing, 100020, China.
Ziying XuCapital Institute of Pediatrics, Beijing, 100020, China.
Zihui YuCapital Institute of Pediatrics, Beijing, 100020, China.
Tongtong FuCapital Institute of Pediatrics, Beijing, 100020, China.
Yanling FengCapital Institute of Pediatrics, Beijing, 100020, China.
Hanqing ZhaoCapital Institute of Pediatrics, Beijing, 100020, China.
Yiming KongCapital Institute of Pediatrics, Beijing, 100020, China.
Xiaohu CuiCapital Institute of Pediatrics, Beijing, 100020, China.
Ziyan TianCapital Institute of Pediatrics, Beijing, 100020, China.
Quanda LiuPostgraduate Base of the PLA Rocket Force Medical Center, Jinzhou Medical University, Jinzhou, 121001, Liaoning Province, China.
Jing YuanCapital Institute of Pediatrics, Beijing, 100020, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer microbiota have recently been demonstrated in several cancer types. The microbiome enhances inflammation in the cancer microenvironment and affects the disease pathology by regulating tumourigenesis, cancer progression, and chemotherapy resistance. Hepatoblastoma (HB), the most common childhood malignant tumour, is a malignant embryonic tumour. However, the pathogenesis and molecular basis of HB remain poorly understood. In this study, to explore the existence and distribution of the microbiome in tumour tissues and adjacent non-tumour tissues of children with HB, we mainly performed 16S rDNA sequencing, and the results showed that the diversity and abundance of the microbiome in children with HB were significantly different between HB tumours and adjacent non-tumour tissues (

Indexed as

ChildrenHepatoblastomaMicrobiomeTumour microenvironment

Identifiers

PMID39553581
PMCPMC11564952

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.