Evidence map›Paper›PMID 39553944›Full record

ArticlebioRxiv : the preprint server for biology2024

Age, sex, and mitochondrial-haplotype influence gut microbiome composition and metabolites in a genetically diverse rat model.

Hoang Van M Nguyen, Eleana Cabello, David Dyer, Chloe Fender, Manuel Garcia-Jaramillo, Norman G Hord, Steven Austad, Arlan Richardson, Archana Unnikrishnan

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Hoang Van M NguyenDepartment of Nutritional Sciences, College of Allied Health, University of Oklahoma Health Sciences, 1200 N Stonewall Ave, Oklahoma City, OK 73117, US.
Eleana CabelloDepartment of Microbiology and Immunology, College of Medicine, University of Oklahoma Health Sciences, Oklahoma City, OK 73117. US.
David DyerDepartment of Microbiology and Immunology, College of Medicine, University of Oklahoma Health Sciences, Oklahoma City, OK 73117. US.
Chloe FenderEnvironmental and Molecular Toxicology, College of Agricultural Sciences, Oregon State University, 2750 SW Campus Way, Corvallis, OR 97331, US.
Manuel Garcia-JaramilloEnvironmental and Molecular Toxicology, College of Agricultural Sciences, Oregon State University, 2750 SW Campus Way, Corvallis, OR 97331, US.
Norman G HordDepartment of Nutritional Sciences, College of Education and Human Sciences, Oklahoma State University, 122 N Monroe St, Stillwater, OK 74075, US.
Steven AustadDepartment of Biology, College of Arts and Sciences, University of Alabama at Birmingham, 902 14 Street South, Birmingham, AL 35205, US.
Arlan RichardsonDepartment of Biochemistry and Physiology, College of Medicine, University of Oklahoma Health Sciences, 975 NE 10 Street, Oklahoma City, OK 73104, US.
Archana UnnikrishnanOklahoma Center for GeroScience and Healthy Brain Aging, University of Oklahoma Health Sciences, 975 NE 10 Street, Oklahoma City, OK 73104, US.

Funding

Proteomics CoreP20GM103447 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI DARRIN R. AKINS · 2012 to 2026
$60.2M
Visualizing insulin actions on neuronal metabolism and function using fluorescent biosensorsP20GM125528 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Veronica Galvan, William Edmund Sonntag · 2019 to 2026
$17.8M
A New Translational Rat Model for Evaluating Anti-Aging InterventionsR33AG072137 · NIA · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI STEVEN N. AUSTAD, ARLAN G. RICHARDSON · 2024 to 2026
$2.2M
Role of DNA Methylation in Dietary Restriction mediated insulin sensitivityK01AG056655 · NIA · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI UNNIKRISHNAN, ARCHANA · 2018 to 2022
$653k
A New Translational Rat Model for Evaluating Anti-Aging InterventionsR21AG072137 · NIA · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI AUSTAD, STEVEN N., RICHARDSON, ARLAN G. · 2022 to 2023
$415k
BLR&D Research Career Scientist Award ApplicationIK6BX005238 · VA · OKLAHOMA CITY VA MEDICAL CENTER · PI ARLAN G. RICHARDSON · 2020 to 2026
–
Effect of Necroptosis in Neurons on Neuroinflammation, Neuronal Function, and CognitionI01BX004538 · VA · OKLAHOMA CITY VA MEDICAL CENTER · PI FREEMAN, WILLARD M, RICHARDSON, ARLAN G. · 2019 to 2024
–
BLRD VA I01 BX004538BLRD VA I01 BX007006BLRD VA IK6 BX005238NIA NIH HHS K01 AG056655NIA NIH HHS R21 AG072137NIA NIH HHS R33 AG072137NIGMS NIH HHS P20 GM103447NIGMS NIH HHS P20 GM125528
6 · The paper itself

Abstract

We evaluated the impact of sex and mitochondrial-haplotype on the age-related changes in the fecal gut microbiome of the genetically heterogeneous rodent model, the OKC-HET

Indexed as

aginggut microbial communityGut microbiomemetabolomicsmitochondriarat

Identifiers

PMID39553944
PMCPMC11565821

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.