Evidence map›Paper›PMID 39554119›Full record

ArticlebioRxiv : the preprint server for biology2025

Large inversions in Lake Malawi cichlids are associated with habitat preference, lineage, and sex determination.

Nikesh M Kumar, Taylor L Cooper, Thomas D Kocher, J Todd Streelman, Patrick T McGrath

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nikesh M KumarSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA.
Taylor L CooperSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA.
Thomas D KocherDepartment of Biology, University of Maryland, College Park, MD USA.
J Todd StreelmanSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA.
Patrick T McGrathSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA.ORCID 0000-0002-1598-3746

Funding

Identification and study of adaptive mutations and phenotypes using laboratory growth of C. elegansR35GM139594 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI MCGRATH, PATRICK T · 2021 to 2025
$2.0M
Cellular basis of complex social behaviorR01GM144560 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI STREELMAN, JEFFERY TODD · 2022 to 2023
$723k
NIGMS NIH HHS R01 GM144560NIGMS NIH HHS R35 GM139594
6 · The paper itself

Abstract

Chromosomal inversions are an important class of genetic variation that link multiple alleles together into a single inherited block that can have important effects on fitness. To study the role of large inversions in the massive evolutionary radiation of Lake Malawi cichlids, we used long-read technologies to identify four single and two tandem inversions that span half of each respective chromosome, and which together encompass over 10% of the genome. Each inversion is fixed in one of the two states within the seven major ecogroups, suggesting they played a role in the separation of the major lake lineages into specific lake habitats. One exception is within the

Identifiers

PMID39554119
PMCPMC11565711

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.