Evidence map›Paper›PMID 39554692›Full record

ArticleNeurophotonics2024

Mapping multi-regional functional connectivity of astrocyte-neuronal networks during behaviors.

Haoyu Wang, Mingzhu Huang, Shaofan Yang, Jiameng Xu, Jin Li, Han Qin, Shanshan Liang, Teng Teng, Chuanyan Yang, Mingyue Gong and 7 more

Abstract read
In one paragraph

Article in Neurophotonics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Haoyu WangThird Military Medical University, Brain Research Center and State Key Laboratory of Trauma and Chemical Poisoning, Chongqing, China.
Mingzhu HuangChongqing University, College of Bioengineering, Chongqing, China.
Shaofan YangThird Military Medical University, Brain Research Center and State Key Laboratory of Trauma and Chemical Poisoning, Chongqing, China.ORCID https://orcid.org/0000-0003-0276-6926
Jiameng XuTiangong University, The School of Control Science and Engineering, Tianjin, China.
Jin LiThird Military Medical University, Brain Research Center and State Key Laboratory of Trauma and Chemical Poisoning, Chongqing, China.
Han QinChongqing Institute for Brain and Intelligence, Guangyang Bay Laboratory, Chongqing, China.ORCID https://orcid.org/0000-0002-9421-5875
Shanshan LiangThird Military Medical University, Brain Research Center and State Key Laboratory of Trauma and Chemical Poisoning, Chongqing, China.
Teng TengThird Military Medical University, Brain Research Center and State Key Laboratory of Trauma and Chemical Poisoning, Chongqing, China.
Chuanyan YangThird Military Medical University, Brain Research Center and State Key Laboratory of Trauma and Chemical Poisoning, Chongqing, China.
Mingyue GongThird Military Medical University, Brain Research Center and State Key Laboratory of Trauma and Chemical Poisoning, Chongqing, China.
Yong HePeking university, School of Electronics, Beijing, China.
Xingyi LiChongqing University, School of Medicine, Center for Neurointelligence, Chongqing, China.ORCID https://orcid.org/0000-0002-9028-1648
Huiquan WangTiangong University, The School of Control Science and Engineering, Tianjin, China.
Xiang LiaoChongqing University, School of Medicine, Center for Neurointelligence, Chongqing, China.ORCID https://orcid.org/0000-0001-6324-5206
Xiaowei ChenThird Military Medical University, Brain Research Center and State Key Laboratory of Trauma and Chemical Poisoning, Chongqing, China.
Zhiqi YangGansu Provincial Central Hospital, Department of Neurology, Lanzhou, China.
Kuan ZhangThird Military Medical University, Brain Research Center and State Key Laboratory of Trauma and Chemical Poisoning, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: Diverse behaviors rely on coordinated activity and multi-regional functional connectivity within astrocyte-neuronal networks. However, current techniques for simultaneously measuring astrocytic and neuronal activities across multiple brain regions during behaviors remain limited. Aim: We propose a multi-fiber solution that can simultaneously record activities of astrocyte-neuronal networks across multiple regions during behaviors. Approach: We employed cell-specific dual-color genetically encoded calcium indicators (GECIs) and multi-fiber photometry to simultaneously measure astrocytic and neuronal Ca Results: Our findings demonstrate that both movements and sensory stimuli induce synchronized and highly correlated Ca Conclusions: Multi-fiber photometry, combined with cell-specific dual-color GECIs, represents a powerful approach for investigating astrocytic and neuronal activities across different brain regions during behaviors. This technique serves as a versatile tool for analyzing the multi-regional functional connectivity map of astrocyte-neuronal networks associated with specific behaviors.

Indexed as

astrocyte-neuronal networksCa2+ transientsfreely movingmulti-fiber photometrymultiple brain regions

Identifiers

PMID39554692
PMCPMC11566604

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.