Evidence map›Paper›PMID 39558241›Full record

ArticleBMC neurology2024

Comparison of functional outcome after intracerebral hemorrhage in patients with or without end stage renal disease on hemodialysis: a propensity-score matched study.

Kotaro Tsutsumi, Matthew Nguyen, Victoria Nguyen, Zhu Zhu, Mohammad Shafie, Jay Shah, Masaki Nagamine, Dana Stradling, Diana Dench, Wengui Yu

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kotaro TsutsumiDepartment of Neurology, University of California, Irvine, 200 S. Manchester Ave. Suite 206, Orange, CA, 92868, USA. ktsutsum@hs.uci.edu.
Matthew NguyenSchool of Medicine, University of California, Irvine, Orange, CA, USA.
Victoria NguyenSchool of Medicine, University of California, Irvine, Orange, CA, USA.
Zhu ZhuDepartment of Neurology, University of Kentucky, Lexington, KY, USA.
Mohammad ShafieDepartment of Neurology, University of California, Irvine, 200 S. Manchester Ave. Suite 206, Orange, CA, 92868, USA.
Jay ShahDepartment of Neurology, University of California, Irvine, 200 S. Manchester Ave. Suite 206, Orange, CA, 92868, USA.
Masaki NagamineDepartment of Neurology, University of California, Irvine, 200 S. Manchester Ave. Suite 206, Orange, CA, 92868, USA.
Dana StradlingDepartment of Neurology, University of California, Irvine, 200 S. Manchester Ave. Suite 206, Orange, CA, 92868, USA.
Diana DenchDepartment of Neurology, University of California, Irvine, 200 S. Manchester Ave. Suite 206, Orange, CA, 92868, USA.
Wengui YuDepartment of Neurology, University of California, Irvine, 200 S. Manchester Ave. Suite 206, Orange, CA, 92868, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnd stage renal disease (ESRD) requiring hemodialysis (HD) increases mortality among patients with intracerebral hemorrhage (ICH). The aim of this study is to investigate the clinical characteristics and outcome of ICH patients with ESRD on HD versus propensity-score matched controls.

methodsThis is a single center retrospective study. Consecutive ICH admissions at the University of California, Irvine Medical Center from January 1, 2018 to July 31, 2022 were analyzed.

resultsAmong 347 ICH admissions that met inclusion criteria, 24 patients (6.92%) had ESRD on HD. Compared to patients without ESRD, patients with ESRD on HD had significantly higher rate of diabetes mellitus (79.2% vs. 36.8%, p < 0.01) and in-hospital mortality (25% vs. 7.43%, p < 0.01). There were no significant differences in demographics, other comorbidities, clinical characteristics, good (mRS score 0-3) or poor (mRS score 4-5) functional outcomes, rate of comfort care and the time to comfort care decision between the 2 groups. After propensity score matching, the ESRD group had a significantly higher in-hospital mortality rate (27.3% vs. 8%, p = 0.012) and a lower rate of obesity (9.1% vs. 34.1%, p = 0.02). Among patients who died during admission, ESRD on HD status did not inadvertently influence end-of-life care decisions. Univariate logistic regression and area under curve analysis showed that ICH score ≥ 3 was a predictor of increased mortality in both ESRD and non-ESRD groups.

conclusionsICH patients with ESRD on HD had significantly higher in-hospital mortality and lower rate of obesity than propensity score matched controls, suggesting a survival benefit from obesity. ICH score ≥ 3 is an independent predictor for poor outcomes in both ESRD and non-ESRD groups.

Indexed as

Cerebral HemorrhageHospital MortalityKidney Failure, ChronicPropensity ScoreRenal DialysisAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeEnd stage renal diseaseHemodialysisIntracerebral hemorrhageMortalityObesity

Identifiers

PMID39558241
PMCPMC11572537

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.