Evidence mapPaperPMID 39559304Full record

ArticleInternational journal of ophthalmology2024

Efficacy of indirect intense pulsed light irradiation on meibomian gland dysfunction: a randomized controlled study.

Yu Cheng, Wen-Jing Song, Mei-Ting Huang, Yuan Gao, Luo-Ying Xie, Ying-Si Li, Song-Lin Yang, Xiao-Ming Yan

Abstract read
In one paragraph

Article in International journal of ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yu ChengDepartment of Ophthalmology, Peking University First Hospital, Beijing 100034, China.
Wen-Jing SongDepartment of Ophthalmology, Peking University First Hospital, Beijing 100034, China.
Mei-Ting HuangDepartment of Ophthalmology, Peking University First Hospital, Beijing 100034, China.
Yuan GaoDepartment of Ophthalmology, Peking University First Hospital, Beijing 100034, China.
Luo-Ying XieDepartment of Ophthalmology, Peking University First Hospital, Beijing 100034, China.
Ying-Si LiDepartment of Ophthalmology, Peking University First Hospital, Beijing 100034, China.
Song-Lin YangDepartment of Ophthalmology, Peking University First Hospital, Beijing 100034, China.
Xiao-Ming YanDepartment of Ophthalmology, Peking University First Hospital, Beijing 100034, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the efficacy and mechanisms of indirect intense pulsed light (IPL) irradiation on meibomian gland dysfunction (MGD).

methodsA total of 60 MGD patients was included in this prospective randomized controlled trial. Patients were randomly assigned 1:1 into two groups (3-mm group and 10-mm group) in which IPL was applied at distances from the lower eyelid margin of 3 and 10 mm, respectively. Both groups received three times treatment with 3-week interval. Meibomian gland yield secretion score (MGYSS), standard patient evaluation of eye dryness (SPEED) questionnaire, tear break-up time (TBUT), corneal fluorescein staining (CFS), and

resultsAfter three IPL treatments, both groups had significant improvement in MGYSS (both

conclusionThe efficacy of IPL indirect irradiation in improving meibomian gland secretion and alleviating dry eye symptoms remains unchanged with increase in treatment distance. IPL may primarily act on the functional improvement of the meibomian glands and corneal nerves.

Indexed as

dry eyeintense pulsed lightmeibomian gland disfunctionocular surface

Identifiers

PMID39559304
PMCPMC11528267

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.