Evidence map›Paper›PMID 39563256›Full record

ArticleBMC musculoskeletal disorders2024

Caffeine intake is nonlinearly associated with muscle mass in young and middle-aged US adults.

Lingling Zhou, Huanjia Qu, Jing Wang, Lan Shou, Qiuling Zhang, Cui Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC musculoskeletal disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lingling ZhouMetabolic Disease Center, Department of Endocrinology and Metabolism, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.
Huanjia QuMetabolic Disease Center, Department of Endocrinology and Metabolism, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.
Jing WangMetabolic Disease Center, Department of Endocrinology and Metabolism, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.
Lan ShouMetabolic Disease Center, Department of Endocrinology and Metabolism, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.
Qiuling ZhangMetabolic Disease Center, Department of Endocrinology and Metabolism, Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China.
Cui ZhangDepartment of Gastroenterology, Shanghai Tenth People's hospital of Tongji University, Shanghai, China. cuicui2056@163.com.ORCID http://orcid.org/0000-0002-6479-6656

Funding

Medical Health Science and Technology Project of Zhejiang Provincial Health Commission 2023RC234National Natural Science Foundation of China 82100545
6 · The paper itself

Abstract

backgroundRecent studies have indicated that coffee consumption is inversely correlated with sarcopenia in the elderly population. Data regarding the association between caffeine intake and muscle mass in young adults are scarce.

objectiveWe aimed to investigate how dietary caffeine correlates with muscle mass and sarcopenia in the young and middle-aged people.

methodsWe performed a cross-sectional study utilizing data from NHANES. Muscle mass was evaluated using DXA and caffeine intake was derived from 24-h dietary recalls. Multivariable regression analysis was adopted to explore association between caffeine and sarcopenia. Restricted cubic spline analysis was conducted to investigate dose-response effect of dietary caffeine on muscle mass. Mediation effect of high-sensitivity C reactive protein was examined by mediation analysis.

resultsA total of 9116 adults aged from 20 to 59 years old were included. Higher ingestion of caffeine was not associated with sarcopenia. Association between dietary caffeine and muscle mass was found to be W-shaped in males and U-shaped in young females, wherein mediation effect of hs-CRP was not discovered.

conclusionsCaffeine consumption is associated with muscle mass in a nonlinear pattern. ASMI peaks at a daily caffeine intake of 1.23 mg/kg in young adults, while 0.64-1.49 mg/kg is recommended for middle-aged men.

Indexed as

CaffeineMuscle, SkeletalNutrition SurveysSarcopeniaAbsorptiometry, PhotonAdultCoffeeCross-Sectional StudiesFemaleHumansMaleMiddle AgedUnited StatesYoung AdultCaffeineCoffeeCaffeineMuscle massNHANESSarcopenia

Identifiers

PMID39563256
PMCPMC11577709

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.