Evidence mapPaperPMID 39563264Full record

ArticleBMC plant biology2024

Melatonin: dual players mitigating drought-induced stress in tomatoes via modulation of phytohormones and antioxidant signaling cascades.

Shifa Shaffique, Anis Ali Shah, Sang-Mo Kang, Md Injamum-Ul-Hoque, Raheem Shahzad, Tiba Nazar Ibrahim Al Azzawi, Byung-Wook Yun, In-Jung Lee

Abstract read
In one paragraph

Article in BMC plant biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Melatonin and Brassinolide Enhance Cold Tolerance inPlants (Basel, Switzerland) · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shifa ShaffiqueDepartment of Applied Biosciences, Kyungpook National University, Daegu, 41566, Republic of Korea.
Anis Ali ShahDepartment of Botany, Division of Science and Technology, University of Education, Lahore, Pakistan.
Sang-Mo KangDepartment of Applied Biosciences, Kyungpook National University, Daegu, 41566, Republic of Korea.
Md Injamum-Ul-HoqueDepartment of Applied Biosciences, Kyungpook National University, Daegu, 41566, Republic of Korea.
Raheem ShahzadDepartment of Horticulture, The University of Haripur, Haripur, Khyber Pakhtunkhwa, 22620, Pakistan.
Tiba Nazar Ibrahim Al AzzawiDepartment of Applied Biosciences, Kyungpook National University, Daegu, 41566, Republic of Korea.
Byung-Wook YunDepartment of Applied Biosciences, Kyungpook National University, Daegu, 41566, Republic of Korea.
In-Jung LeeDepartment of Applied Biosciences, Kyungpook National University, Daegu, 41566, Republic of Korea. ijlee@knu.ac.kr.

Funding

Korea Brain Research Institute bk21
6 · The paper itself

Abstract

Drought stress significantly retards the plant production. Melatonin is a vital hormone, signaling molecule, and bio-regulator of diverse physiological growth and development processes. Its role in boosting agronomic traits under diverse stress conditions has received considerable attention. However, the underlying molecular mechanism of action and how they increase drought stress tolerance has not been fully interpreted. The current study aimed to ascertain the protective role of melatonin in fortifying the antioxidant defense system, modulating the phytohormone profile, and improving agronomic traits of tomato seedlings under drought stress. After the V1 stage (1st leaf fully emerged), tomato seedlings were exposed to PEG-6000 to mimic drought-induced stress (DR 10% and DR 20%), followed by exogenous application of 100 µM soil drench. Drought-induced stress negatively impacted tomato seedlings by reducing growth and development and biomass accumulation, diminishing salicylic acid (SA) and chlorophyll levels, and dramatically lowering the antioxidant defense ability. However, melatonin protected them by activating the defense system, which decreased the oxidative burst and increased the activities of SOD, CAT, and APX. Administration of 100 µM melatonin by soil drench most remarkably downregulated the transcription factors of SlDREB3 and SlNCED3. This study has validated the moderating potential of melatonin against drought-induced stress by maintaining plant growth and development, enhancing hormone levels, elevating antioxidant enzyme activities, and suppressing the relative expression of drought-responsive genes. These findings also provide a basis for the potential use of MT in agricultural research and other relevant fields of study.

Indexed as

AntioxidantsDroughtsMelatoninPlant Growth RegulatorsSignal TransductionSolanum lycopersicumGene Expression Regulation, PlantSeedlingsStress, PhysiologicalAntioxidantsMelatoninPlant Growth RegulatorsABAAntioxidantsMelatoninSATranscription factors

Identifiers

PMID39563264
PMCPMC11577958

What Socratic holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.